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Diagnosis of Pulmonary Embolism Using D-Dimer Thresholds Selected According to Clinical Pre-Test Probability
ISTH Academy, Kerstin de Wit, 273910
Development of a Formulation for Oral Delivery of FVIII via a Robotic Pill
ISTH Academy, Gerald Schrenk, 273977
A Test of the GPIbα β-switch Hypothesis for Platelet-type von Willebrand Disease
ISTH Academy, Matthew Auton, 274089
Knockout of von Willebrand Factor in Zebrafish by CRISPR/Cas9 Mutagenesis
ISTH Academy, Pudur Jagadeeswaran, 274121
Welcome and Introduction
ISTH Academy, Chris Barnes, 274975
The Multi-Functional Role of FVIII
ISTH Academy, Johannes Oldenburg, 274976
Emerging Clinical Evidence
ISTH Academy, Ingrid Pabinger-Fasching, 274977
Optimization of Patient Management via WAPPS
ISTH Academy, Alfonso Iorio, 274978
Q&A and Close
ISTH Academy, Session Speakers, 274979
Safety of Dabigatran Etexilate for Secondary Prevention of Venous Thromboembolism in Paediatric Patient
ISTH Academy, Leonardo Brandao, 273755
Efficacy and Safety of Dabigatran Etexilate for Treatment of Venous Thromboembolism in Paediatric Patients - Results of the DIVERSITY Trial
ISTH Academy, Manuela Albisetti, 273756
Novel Single Cell Mechanobiology Approach Reveals an Intermediate State of Integrin αIIbβ3 that Mediates Platelet Aggregation under Blood Flow Disturbance
ISTH Academy, Lining Arnold Ju, 273760
Recombinant Canine and Human FXa-I16LProvide Safe and Efficacious Hemostasis during Major Bleeding Events in Hemophilia A Dogs with High-titer Inhibitory Anti-FVIII Antibodies
ISTH Academy, Timothy Nichols, 273762
Proteomic Analysis Reveals Age-Specific Global Changes in Platelet, Plasma and Endothelial Haemostatic Proteins
ISTH Academy, Conor McCafferty, 273773
The Imbalanced Hepatic Production of PAI1 and tPA Contributes to Decreased Fibrinolysis in Obesity
ISTH Academy, Ze Zheng, 273781
Retrospective Review of Outcomes and Anticoagulation use for Elderly Patients that Present with an Acute Hip Fracture at Three Tertiary Hospitals in Perth, Western Australia
ISTH Academy, Katherine Creeper, 273789
Novel Plasmin Generation Assay Reveals a Plasminogen Activator Inhibitor-1-Independent Mechanism That Contributes to the Hemostatic Imbalance in Experimental Obesity
ISTH Academy, Adam Miszta, 273798
Investigation of the Age-specific in vitro Effect of Bivalirudin in Children Compared to Adults
ISTH Academy, Xavier Busuttil-Crellin, 273805
Investigations of the von Willebrand Factor (VWF) p.Arg273Trp Variant Using Endothelial Colony Forming Cells (ECFCs)
ISTH Academy, Mackenzie Bowman, 273814
Neither a Structured Questionnaire at Pre-anesthesia Visit Nor the Prescription of Routine Hemostatic Tests Have Acceptable Performances to Detect Hemostatic Abnormalities before Surgery
ISTH Academy, Nadine Ajzenberg, 273826
Effect of DOAC Type and DOAC Dose, and Residual DOAC Level on Risk for Perioperative Major Bleeding and Arterial Thromboembolism
ISTH Academy, James Douketis, 273835
Retrospective Analysis of the Clinical Effectiveness of a Reduced Dose of Idarucizumab in Dabigatran Reversal
ISTH Academy, Louisa Stone, 273844
Sodium-calcium Exchanger Reverse Mode is Required for Generation of Procoagulant COAT Platelets
ISTH Academy, Alessandro Aliotta, 273847
FcγRIIa Polymorphisms and Allele-Specific Haplotypes in Heparin-Induced Thrombocytopenia (HIT)
ISTH Academy, Christine Lee, 273868
Extensive Tyrosine Phosphoproteomic Analysis of the CLEC-2 Signalling Cascade in Human Platelets: New Players on the Team
ISTH Academy, Maria Nuñez Barrachina, 273887
Characterization of a Novel GPIbα Knockin Mouse that Lacks the Last 24 Amino Acids of its Intracellular Domain
ISTH Academy, Isabelle Salles-Crawley, 273898
Identification and Characterization of Murine FVIII-producing Cells in vivo
ISTH Academy, Morisada Hayakawa, 273925
The Rare MAST2 Arg89Gln Mutation Causes Venous Thrombosis in a French Family with Unexplained Thrombophilia: The Breizh MAST2 Mutation
ISTH Academy, Pierre Emmanuel Morange, 273927
The Route of FVIII Endocytosis by Antigen-presenting Cells Determines the Pattern of FVIII Peptide-specific T Cells Activation
ISTH Academy, birgit reipert, 273937
TMT-based Temporal Quantitative Phosphoproteome of Human Platelets in Response to Collagen
ISTH Academy, Peng Jiang, 273941
Hepatic Thrombopoietin Gene Silencing Induces Platelet Count Reduction within the Hemostatic Range and Reduces Breast Cancer Progression in MMTV-PyMT Mice
ISTH Academy, Toshiaki Shirai, 273944
Exploring Spontaneous Readthrough over Recurrent F8 Nonsense Mutations: Potential Correlation with Inhibitor Risk?
ISTH Academy, Silvia Lombardi, 273947
Decoding Gαq Signaling in Platelets
ISTH Academy, Peisong Ma, 273956
Activated Thrombin Activable Fibrinolysis Inhibitor (TAFIa) Regulates Plasmin Generation on Thrombin-activated Platelets
ISTH Academy, Paul Kim, 273964
Comparison of Stroke Incidence in Fontan Patients Receiving Warfarin or Aspirin
ISTH Academy, Chantal Attard, 273989
Increased in vivo Angiogenesis in von Willebrand Factor (VWF)-deficient Mice
ISTH Academy, Soundarya Selvam, 273994
An Engineered Protein Analogous to IL-2, Mutein 24, Decreases the Formation of Factor VIII Inhibitors in Hemophilia Mice Receiving Factor VIII Treatment
ISTH Academy, Alex Chen, 273999
Anti Platelet Antibodies Predict Platelet Desialylation and Apoptosis in ITP
ISTH Academy, Shiying Silvia Zheng, 274001
A Dysbiotic Gut Microbiota Diminishes Short-Chain Fatty Acid Production and Increases Factor VIII Immunogenicity in Haemophilia A Mice
ISTH Academy, Matthew Cormier, 274002
In vivo Enrichment of Genetically Manipulated Platelets for Murine Haemophilia B Gene Therapy
ISTH Academy, Yingyu Chen, 274006
Allele-specific Inhibition of VWF p.Cys1190Tyr in Patient-Derived Endothelial Colony Forming Cells Corrects the von Willebrand Disease Type 2A Phenotype
ISTH Academy, Annika de Jong, 274012
Development and Validation of a Plasma micro-RNAs Profile Associated with Venous Thrombosis
ISTH Academy, José Manuel Soria, 274014
Efficacy and Safety of Prothrombin Complex Concentrate in Patients with Intracranial Bleeding Treated with Factor Xa Inhibitors and Patients Treated with Vitamin K Antagonists
ISTH Academy, Roisin Bavalia, 274015
In vitro and in vivo Amelioration of the von Willebrand Disease Type 2B Phenotype Using an Allele-specific siRNA
ISTH Academy, Annika de Jong, 274017
Generating Plasma Protein Signatures for Murine Venous Thrombosis and Slc44a2 Deficiency Using a Multiplex Targeted Proteomics Approach
ISTH Academy, Julia Tilburg, 274019
High-throughput Immunoprofile Mimotope Variation Analysis in Previously Untreated Patients with Severe Haemophilia A before and after FVIII Exposure
ISTH Academy, Roberta Palla, 274024
Shear Rate Gradients Promote a Bi-phasic Thrombus Formation in a Vwf-dependent Manner
ISTH Academy, Nicolas Receveur, 274034
Platelet-dependent Activation of Thrombin-activatable Fibrinolysis Inhibitor (TAFI)
ISTH Academy, Yuko Suzuki, 274047
Large Gene Deletion in a VWD Patient Impairs VWF Storage in WPBs and Affects Phenotypic Features of Blood Outgrowth Endothelial Cells
ISTH Academy, Hamideh Yadegari, 274055
Targeting Thrombolytics for Thrombotic Thrombocytopenic Purpura
ISTH Academy, Steven de Maat, 274063
Plasma-derived FVIII/VWF Combined with Emicizumab in Hemophilia A Plasma with and without Inhibitor Has a Non-additive Effect on in vitro Thrombin Generation
ISTH Academy, Maria Isabel Bravo, 274071
Clinical Association of Increased Antioxidant Enzymes Levels in Immune Thrombocytopenic Purpura
ISTH Academy, Aisha Arshad, 274072
Immune Phenotyping Predicts Prognosis and Treatment Response in Newly Diagnosed Childhood Immune Thrombocytopenia
ISTH Academy, David Schmidt, 274076
Differential Production of Cytokines in Response to FVIII in Hemophilia Patients Undergoing ITI: A Preliminary Analysis of a Multi-center Longitudinal Study
ISTH Academy, Davide Matino, 274079
Feasibility of a New, Rapid Functional Assay for the Diagnosis of Heparin-induced Thrombocytopenia: A Standardized Flow Cytometry Assay
ISTH Academy, Justine Brodard, 274092
Curating Disease-causing Genes for Bleeding, Thrombotic and Platelet Disorders, and Application to the ThromboGenomics Gene Panel Test
ISTH Academy, Karyn Megy, 274107
Platelet mRNA Splicing Landscape and its Effect on Platelet Activity: An ACCOuNT Consortium Study
ISTH Academy, Kaitlin Garofano, 274130
Antithrombin Activity Levels Below 60% in Children Less than 1 Month of Age Have Implications for Heparin (LMWH) Dosing
ISTH Academy, Irene Regan, 274136
FcγRIIa Polymorphisms and Allele-Specific Haplotypes in Heparin-Induced Thrombocytopenia (HIT)
ISTH Academy, Christine Lee, 275121
In vivo Enrichment of Genetically Manipulated Platelets for Murine Haemophilia B Gene Therapy
ISTH Academy, Yingyu Chen, 275124
Generating Plasma Protein Signatures For Murine Venous Thrombosis and Slc44a2 Deficiency Using a Multiplex Targeted Proteomics Approach
ISTH Academy, Julia Tilburg, 275125
Increased in vivo Angiogenesis in von Willebrand Factor (VWF)-deficient Mice
ISTH Academy, Soundarya Selvam, 275126
Investigations of the von Willebrand Factor (VWF) p.Arg273Trp Variant Using Endothelial Colony Forming Cells (ECFCs)
ISTH Academy, Mackenzie Bowman, 275127
Novel Single Cell Mechanobiology Approach Reveals an Intermediate State of Integrin αIIbβ3 that Mediates Platelet Aggregation under Blood Flow Disturbance
ISTH Academy, Lining Arnold Ju, 275129
Decoding Gαq Signaling in Platelets
ISTH Academy, Peisong Ma, 275132
Immune Thrombosis From a Clinical Perspective
ISTH Academy, Sam Schulman, 275191
Combining Antiplatelet and Anticoagulant Therapy
ISTH Academy, John Eikelboom, 275192
Risk Stratification of Patients with Acute PE: Implications for Home Treatment and Reperfusion Strategies
ISTH Academy, Stefano Barco, 275193
Platelet Microparticles and Inflammatory Diseases
ISTH Academy, Eric Boilard, 275194
Activation and Regulation of the Thrombopoietin Receptor
ISTH Academy, Ian Stuart Hitchcock, 275201
VKA are the Anticoagulant of Choice for Mechanical Valves in Pregnancy (Debate)
ISTH Academy, Claire McLintock, 275203
VKA are the Anticoagulant of Choice for Mechanical Valves in Pregnancy (Debate)
ISTH Academy, Dominica Zentner, 275204
Diagnosis of PE in Pregnancy
ISTH Academy, Grégoire Le Gal, 275205
Spatiotemporal Regulation of Plasminogen Activation and its Disruption
ISTH Academy, Tetsumei Urano, 275208
Fibrin/ogen Structure as a Potential Therapeutic Target
ISTH Academy, Alisa Wolberg, 275209
ADAMTS13 and VWF in TTP
ISTH Academy, José López, 275210
Modifiers and Genetics of VWF
ISTH Academy, Jill Johnsen, 275212
Development of a laser-induced thrombosis model with improved reproducibility allows detailed analysis of dose-response effects of antithrombotic drugs
ISTH Academy, PIa Larsson, 263797
Pathophysiological implications of differential coagulotoxic effects of Bitis viper snake venoms
ISTH Academy, Nicholas Youngman, 263815
Mechanism Of Activation Of The Intrinsic Pathway of Coagulation By Microvesicles Isolated From Red Cell Concentrates
ISTH Academy, Anton Ilich, 263833
Intra-assay reproducibility of a precalibrated liquid Clauss fibrinogen assay
ISTH Academy, Audrey Carlo, 263850
Thrombin-cleaved Osteopontin Enhances B16 Melanoma Growth
ISTH Academy, John Morser, 263868
Chest wall haemophilic pseudo tumour in a patient with severe Haemophilia A with inhibitor: A case report
ISTH Academy, Melanie Jackson, 263884
Ideal Body Weight Is Proven Most Reliable to Dose Factor VIII Concentrate in Overweight and Obese Hemophilia A Patients
ISTH Academy, Iris Van Moort, 263900
The rate of factor VIII inhibitors and mutation profile in Polish previously untreated patients (PUPs) on prophylaxis with octocog-alfa
ISTH Academy, Andrzej Koltan, 263916
The first Chinese hemophilia individualized prophylaxis study (CHIPS) : Improvement in Health-Related Quality of Life (HRQoL) CHO-KLAT scores in boys with severe hemophilia A in China
ISTH Academy, Runhui Wu, 263933
CONGENITAL FACTOR XI DEFICIENCY, INHIBITOR AND CLOT FORMATION
ISTH Academy, Erica Scalambrino, 263950
DELPHI expert consensus statements on clinical evaluation of bleeds in patients with acquired haemophilia
ISTH Academy, Andreas Tiede, 263966
Effect of pathologic flow on von Willebrand factor cleavage by ADAMTS13
ISTH Academy, Maria Bortot, 263983
Association of easy bruising with female gender: a prospective cohort study
ISTH Academy, Michael Nagler, 263999
A Qualitative Analysis on Patient Understanding with Anticoagulation Use & Indication and the Effect of Nurse Practitioner Led Patient Education
ISTH Academy, Laurie Sardo, 264018
Acquired von Willebrand syndrome (aVWS) - a complication in pediatric patients with congenital heart diseases
ISTH Academy, Ivonne Wieland, 264036
Highly discordant laboratory-based aspirin resistance rates after pediatric organ transplantation may reflect significant cyclooxygenase 1-independent thromboxane production postoperatively
ISTH Academy, Lori Luchtman-Jones, 264052
A Retrospective Review of Antithrombotic Therapy in Paediatric Patients with Moyamoya Disease
ISTH Academy, Nadia Poci, 264068
Analysis of Stroke in Neonates and Children: Single Center Experience
ISTH Academy, Hale Ören, 264085
Effective and well tolarated treatment with a direct oral anticoagulant in a young patient with the vena cava inferior agenesis and a deep vein thrombosis
ISTH Academy, Tomas Kuhn, 264102
Bleeding phenotype of patients with congenital platelet defects
ISTH Academy, Rolf Urbanus, 264119
MYH9 Disorders in Thailand: Pediatric Case Series from Thai Macrothrombocytopenia Study Group
ISTH Academy, Rungrote Natesirinilkul, 264135
Post-translational polymodification of the C-terminal tail of TubB1 regulates motor protein activity in platelet production and function
ISTH Academy, Neil Morgan, 264152
Variation of platelet dependent thrombin generation in phenotypes of acute venous thromboembolism
ISTH Academy, Marina Panova-Noeva, 264169

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