ISTH Academy

This live session will be hosted on:
July 31, 2024 14:00-15:00 UTC

Session Description: 
This webinar will feature talks by Dr. Mary-Carmen Amigo and Dr. Scott Woller discussing new insight in diagnosis and treatment of antiphospholipid syndrome.

Event Outline:

• Introduction by Anna Parks, M.D.
• 2023 ACR/EULAR Antiphospholipid Syndrome Classification Criteria by Mary-Carmen Amigo, M.D. (20 minutes)
• Is there a role for direct oral anticoagulants in the treatment of antiphospholipid syndrome? by Scott Woller, M.D. (20 minutes)
• Q&A with audience (15 minutes)

Learning Objectives: 

2023 ACR/EULAR Antiphospholipid Syndrome Classification Criteria 

• Differentiate between classification and diagnostic criteria
• Discuss how to accurately interpret the 2023 ACR/EULAR APS Classification criteria for research purposes
• Consider classification criteria are not for diagnosis and treatment in daily practice

Is there a role for direct oral anticoagulants in the treatment of antiphospholipid syndrome? 

• Understand the historical role of anticoagulation and thrombotic APS
• Review clinical trials that assessed the comparative safety and effectiveness of DOACs with BKA for the treatment of thrombotic APS
• Discuss how to interpret results and effectiveness of DOACs with BKA for the treatment of thrombotic APS
• Understand cliinical guidance surrounding best practice for the treatment of thrombotic APS

Supported by Werfen

Session Description: 
This webinar will feature talks by Dr. Fraser Macrae and Dr. Valerie Tutwiler discussing fibrin formation and fibrinolysis testing in research.

Event Outline:

• Introduction by Tirsa van Duijl, Ph.D.
• Microscopy approaches to study fibrin by Fraser Macrae, Ph.D. (20 minutes)
• In vitro assays to study fibrin formation and FXIII crosslinking by Valerie Tutwiler, Ph.D. (20 minutes)
• Q&A with audience (15 minutes)

Learning Objectives

Microscopy Approaches to Study Fibrin

• Understand why we study changes in fibrin clot structure
• Understand how multiple microscopy methods can be used to investigate fibrin clot structure

In vitro assays to study fibrin formation and FXIII crosslinking

• Review techniques that can be utilized to assess dynamic changes in clo formation/dissolution
• Determine the best technique for looking at changes in clotting kinetics and structure