Thromboprophylaxis in pregnant women: For whom and which LMWH dosage? Reply

ISTH Academy, Claire Mclintock, 278064

ISTH News and Updates: Join the ISTH Today

ISTH Academy, Faculty / Presenter(s), 278080

Diagnostic and Score Value of Ultrasound and Magnetic Resonance Imaging in Hemophilia Arthropathy

ISTH Academy, Fei Ma, 273745

Olfactory Receptors and Dysregulated Platelet Activity in Abdominal Aortic Aneurysms

ISTH Academy, Scott Cameron, 273752

The Thrombocytopathy in the Netherlands Study: A Horizontal Diagnostic Approach for Suspected Congenital Platelet Defects

ISTH Academy, Rolf Urbanus, 273754

Joint Bleeds in Paediatric Patients with Haemophilia A: A CHESS Study Analysis

ISTH Academy, Jamie O’Hara, 273785

Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of ACT017, an Anti-platelet Glycoprotein VI Fab: First in Human Healthy Volunteer Trial

ISTH Academy, Martine Jandrot-Perrus, 273796

Novel Murine Venous Thromboembolism Model to Evaluate Role of Factor XIII in Pulmonary Embolism Risk

ISTH Academy, Sravya Kattula, 273797

Characterization of Factor VIII Binding Sites on the Low-density Lipoprotein Receptor-related Protein 1 (LRP) Suggests a Dynamic Bivalent Mode of this Interaction

ISTH Academy, Andrey Sarafanov, 273815

Identification and Functional Characterization of a New Thrombus-resolving Regulatory T-cell Population

ISTH Academy, Fatemeh Shahneh, 273833

Confirmation of ACTN1 Variants as the Cause of Macrothrombocytopenia Using an in Vitrocellular Model

ISTH Academy, Yuki Takagi, 273840

Variants from Patients with Hemophilia Impair Proper Carboxylation of Factor IX

ISTH Academy, Nicholas Popp, 273845

Neutrophils Prothrombotic Characteristics during Myeloproliferative Neoplasms

ISTH Academy, Chloe James, 273861

Association of Body Weight with Efficacy and Safety of Apixaban and Rivaroxaban in Relation to Low Molecular Heparin and Vitamin K Antagonists in Acute Venous Thromboembolism

ISTH Academy, Waldemar Wysokinski, 273862

Isolation of Silica-free DNA and Studies of its Effects on Organ Damage in Mice

ISTH Academy, Sarah Medeiros, 273867

The Fibrin αC Region is Critical for Mechanical Strength, Resistance to Fibrinolysis and the Formation of a Stable Whole Blood Clot

ISTH Academy, Helen McPherson, 273873

Targeting Protease Nexin-1, a Natural Anticoagulant, to Control Bleeding in Hemophilia A

ISTH Academy, Karen Aymonnier, 273874

Efficacy and Safety of BAY 94-9027 is Sustained for 5 Years: Outcomes in 36 Patients in the PROTECT VIII Extension Study

ISTH Academy, Mark T. Reding, 273894

Ceramide 1 Phosphate Is a Potent Chemoattractant Factor of Endothelial Colony Forming Cells and Improve Post Ischemia Tissue Regeneration

ISTH Academy, Hebe Agustina Mena, 273904

Endothelial Plasminogen Activator Inhibitor-1 Blocks the Intrinsic Pathway of Coagulation, Inducing the Clearance and Degradation of Activated Factor XI

ISTH Academy, Cristina Puy, 273906

Coagulation Activation Induced by Platelet-Derived Microvesicles is Mediated by Kallikrein-Dependent Activation of Factor IX

ISTH Academy, Nigel Key, 273908

Thrombus Resolution in Splanchnic Vein Thrombosis

ISTH Academy, Ana Isabel Casanegra, 273917

Two Birds, One Stone: Anti-β3 Integrin PSI Domain Antibodies Inhibit Both Platelet Aggregation and Blood Coagulation

ISTH Academy, Miguel Neves, 273921

Factor VIII (FVIII)-Haplotype Mismatch Increases Risk of Inhibitor Development in the Treatment of Hemophilia A (HA)

ISTH Academy, Tom Howard, 273928

Use of Direct Oral Anticoagulants in Patients with Different Types of Hereditary Thrombophilia: A Retrospective Cohort Study

ISTH Academy, Elena Campello, 273932

Unexpected Enhancement of FVIII Immunogenicity by Endothelial Expression in Lentivirus-transduced and Transgenic Mice

ISTH Academy, Qizhen Shi, 273938

Extended Stability of Activated TAFI Normalizes Vascular Dysfunction in Hemophilic Joint Disease in Mice

ISTH Academy, Tine Wyseure, 273940

Spontaneous Bleeding and Poor Bleeding Response with Extended Half-life Factor IX Products: A Survey of Select US Hemophilia Treatment Centers

ISTH Academy, Robert Fran Sidonio Jr., 273953

DOAC Plasma Concentrations in High Weight Patients: An Observational Study

ISTH Academy, Anne Celine Martin, 273958

Targeting Activated Platelets in the Tumor Microenvironment for Localized Delivery of Antibody-drug Conjugates to Tumors and Metastases

ISTH Academy, James McFadyen, 273990

Australian and New Zealand Registry of Anticoagulation in the Obese

ISTH Academy, Georgia McCaughan, 274005

First Generation PI3KC2α Inhibitors are Potently Anti-Thrombotic and Improve on the Safety Profile of Current Anti-Platelet Therapies

ISTH Academy, Mitchell Moon, 274013

Transforming Growth Factor β Released by Platelets Primes Macrophage Activation and Extracellular Trap Formation, Thereby Influencing Breast Cancer Growth in Mice

ISTH Academy, Elmina Mammadova-Bach, 274035

Inhibition of Platelet GPVI Induces Intratumor Hemorrhage and Increases Efficacy of Chemotherapy in Mice

ISTH Academy, Julia Volz, 274053

New Constitutional GATA1 Variants Study Reveals the Contribution of GATA1 in MYH10 Silencing During Megakaryopoiesis

ISTH Academy, Paul Saultier, 274054

High-molecular-Weight Kininogen Is a Critical Component of Host Defense against Gram-negative Bacteria: Evidence from a Humanized HK Mouse Model

ISTH Academy, Aizhen Yang, 274059

Factor XII-W268R, a Human Mutation Causing Autoinflammation, Accelerates Activation through Exposure of the Activation Loop

ISTH Academy, Chantal C Clark, 274060

Venous Thrombosis and Thrombocyte Activity in Zebrafish Models of Quantitative and Qualitative Human Fibrinogen Disorders

ISTH Academy, Cristina Freire Sanz, 274062

Recombinant Factor VIII Fc Fusion Protein Inhibits Inflammatory Osteoclast Formation in vitro

ISTH Academy, Robert Peters, 274074

Detection and Analysis of Gene Mutations in Patients with Fibrinogen Deficiency by Next Generation Sequencing

ISTH Academy, Boyang Sun, 274085

A RNA Interference-based Approach to Autosomal Dominant Glanzmann Thrombasthenia: A Step towards Personalized Treatment

ISTH Academy, Loredana Bury, 274096

Characterization of Blood Outgrowth Endothelial Cells (BOECs) from Hermansky-Pudlak Syndrome (HPS) Type 1

ISTH Academy, Giulio Purgatorio, 274099

Impaired Hemostatic Activity of Healthy Transfused Platelets in Select Inherited Platelet Disorders: Mechanisms and Implications

ISTH Academy, Robert Lee, 274106

Blood Endothelial Progenitor Cell-on-a-Chip: A Disease and Patient-specific Cell Source for in vitro Vascular Tissue Engineered Platforms

ISTH Academy, Tanmay Mathur, 274111

Novel NADPH Oxidase 1-selective Inhibitors Impair Collagen-dependent Platelet Activation and Thrombus Formation in vitro and Ferric Chloride-induced Carotid Occlusion in vivo with Negligible Effects on Thrombin Responses and Bleeding Time

ISTH Academy, Giordano Pula, 274116

Understanding the Chromatin Regulatory Landscape Controlling Fibrinogen Gene Expression

ISTH Academy, Richard J. Fish, 274117

Hemarthrosis in FVIII-deficient Mice Causes Altered Expression of Local and Systemic Iron Regulators and Defective Iron Clearance from the Joint

ISTH Academy, Annette von Drygalski, 274128

Targeting Protein S Protects Mice with Hemophilia A from Acute and Chronic Hemartrosis

ISTH Academy, Raja Prince, 274131

Suppression of FVIII-specific Memory B Cells by Regulatory T Cells Expressing BARs

ISTH Academy, Ai-Hong Zhang, 274138

Intracranial Hemorrhage in Hemophilia - A Systematic Review

ISTH Academy, AnneFleur Zwagemaker, 274141

The Fibrin αC Region is Critical for Mechanical Strength, Resistance to Fibrinolysis and the Formation of a Stable Whole Blood Clot

ISTH Academy, Helen McPherson, 275139

First Generation PI3KC2α Inhibitors are Potently Anti-Thrombotic and Improve on the Safety Profile of Current Anti-Platelet Therapies

ISTH Academy, Mitchell Moon, 275142

Two Birds, One Stone: Anti-β3 Integrin PSI Domain Antibodies Inhibit Both Platelet Aggregation and Blood Coagulation

ISTH Academy, Miguel Neves, 275143

Anticoagulant-Associated Bleeding in AF Patients

ISTH Academy, Elaine Hylek, 275214

Triple Therapy in Patients with Atrial Fibrillation and Acute Coronary Syndrome or PCI/Stenting

ISTH Academy, Gregory Lip, 275215

Structure and Function of FXI/FXII

ISTH Academy, Jonas Emsley, 275217

Clinical Trials with FXI Inhibitors

ISTH Academy, Jeffrey Weitz, 275218

Mechanisms of Fc-Independent Thrombocytopenia

ISTH Academy, Heyu Ni, 275219

Thrombopoietin Receptor Agonists

ISTH Academy, David Kuter, 275220

Thrombocytopenia in Pregnancy

ISTH Academy, Terry Gernsheimer, 275221

Thrombogenomics

ISTH Academy, Keith Gomez, 275222

Epigenetics in Hemostasis

ISTH Academy, Elisa Danese, 275223

Platelet Proteome

ISTH Academy, Jonas Enrique Perales Aguilar, 275224

Cryopreserved Platelets in Trauma

ISTH Academy, Michael Reade, 275225

Tranexamic Acid: An Effective Treatment for Acute Severe Bleeding

ISTH Academy, Ian Roberts, 275226

Molecular Links Between Coagulation and Innate Immunity

ISTH Academy, Edward Conway, 275228

Endothelial Cell Contribution to the Pathology in HIT

ISTH Academy, Lubica Rauova, 275229

Management Strategies for Hematological Derangement in Dengue Hemophilia Fever

ISTH Academy, Ampaiwan Chuansumrit, 275231

Hemostasis in Liver Disease

ISTH Academy, Maria Magnusson, 275232

Late Breaking Abstracts

ISTH Academy, Faculty / Presenter(s), 277633

Late Breaking Abstracts

ISTH Academy, Faculty / Presenter(s), 286347

The mortality outcomes and survival patterns of myeloproliferative neoplasm registry in Malaysia

ISTH Academy, Yee Yap, 264345

Rheological and Hemostatic Aspects of Venous Thromboembolism in Patients with Severe Stroke

ISTH Academy, Kostiantyn Stepanchenko, 264368

Mapping of coagulation factor IX binding site on Collagen Toolkits II, III and XIII

ISTH Academy, Samir Hamaia, 264385

Coagulation status of critically ill patients with liver disease assessed using a novel thrombin generation analyser

ISTH Academy, Gael B Morrow, 264402

New functional test for the TFPIα cofactor activity of Protein S working in synergy with FV-Short

ISTH Academy, Björn Dahlbäck, 264420

Antiphospholipid antibodies and thrombosis in BCR-ABL negative myeloproliferative neoplasms

ISTH Academy, Rolandas Gerbutavičius, 264440

Evaluation of hemostasis in patients with Alzheimer´s disease and frontotemporal dementia by thrombin generation test

ISTH Academy, Luci Dusse, 264459

Auto- or Allo-Antibodies to hemostasis Proteins and their Patho-Physiological Effects

ISTH Academy, Jean Amiral, 264476

Variation in one-stage coagulation reagents in FIX Extended Half-life product measurements in External Quality Control Assessment programs

ISTH Academy, Moniek De Maat, 264492

Effects of clopidogrel versus ticagrelor on platelet function in patients undergoing percutaneous coronary intervention: assessed by light transmission aggregometry, vasodilator-stimulated phosphoprotein assay and mean platelet volume

ISTH Academy, Yang Zhang, 264510

Fibrinolysis patterns of different plasminogen mutant proteins in patients with inherited plasminogen deficiency: impact on the development of ligneous conjunctivitis

ISTH Academy, Nadine Ajzenberg, 264530

A new treatment for thrombosis prevention?

ISTH Academy, PIa Larsson, 264549

Peptidomics of metalloproteinase-induced haemorrhage: insights from the analysis of the degradation of components of the mouse skin and human plasma by the snake venom metalloproteinase HF3

ISTH Academy, Solange M T Serrano, 264567

A validation study of plasminogen activator inhibitor-1 as a predictive marker of mortality in sepsis

ISTH Academy, Kota Hoshino, 264584

Clinical characteristics and incidence of inhibitors in patients with haemophilia: results of the HEMILcohort study

ISTH Academy, Letícia Lemos Jardim, 264601

Effectiveness and Safety of Real-World Treatment with BAY 94-9027 in Previously Treated Patients with Hemophilia A: Rationale and Design of the HEM-POWR Study

ISTH Academy, Martin Sanabria, 264617

SEROPREVALENCE AND CLINICAL CHARACTERISTICS OF VIRAL HEPATITIS IN HEMOPHILIA PATIENTS

ISTH Academy, Fahri Şahin, 264634

Comparative pharmacokinetic study between Alphanate and Octanate using WAPPS-Hemo

ISTH Academy, Santiago Bonanad, 264650

Dynamic coagulability during cardiovascular surgery and its correlations with bleeding volume

ISTH Academy, Satoshi Fujii, 264670

von Willebrand factor in experimental malaria-associated acute respiratory distress syndrome

ISTH Academy, Sirima Kraisin, 264686

Platelets and coagulation mediate bacterial adhesion to damaged and inflamed heart valves in Staphylococcus aureus endocarditis

ISTH Academy, Severien Meyers, 264704

The highly efficacious antithrombotics act as selective inhibitors of αIIbβ3 outside-in signaling with a high safety profile

ISTH Academy, Tur-Fu Huang, 264720

The rate of platelet activation varies within the normal population and does not correlate with maximal levels of platelet activation

ISTH Academy, Joanne Mitchell, 264738

Redox Based Regulation of GPVI-mediated Platelet Function: Role for S-Glutathionylation

ISTH Academy, Amandeep Kaur, 264754

Clinical safety of therapeutic plasma exchange with fresh frozen plasma inactivated with Mirasol PRT system in patients with acquired TTP

ISTH Academy, Magdalena Letowska, 264773

Abnormal ADAMTS13 and chemotherapy-associated thrombosis in women with ovarian cancer

ISTH Academy, Alexander Vorobev, 264790

Bovine and Porcine Mucosal Heparins Exhibit Comparable Pharmacodynamic Behaviors at USP Potency Adjusted Doses

ISTH Academy, Ahmed Kouta, 264806

An Exploration of the Psychological Impact of Pulmonary Embolism

ISTH Academy, Anna Tran, 264824

Analysis of Central Venous Catheter Preservation on Prophylactic Rivaroxaban in the CASSINI Study

ISTH Academy, Gerald Soff, 264840