PB0744 Examining the Effect of Chemotherapy on Platelet Count and Function in Women with Cancer

ISTH Academy, Faculty / Presenters, 407130

PB0741 Plasma Podoplanin is Increased in Newly Diagnosed Acute Promyelocytic Leukemia Compared to Other Types of Acute Myeloid Leukemia and Associates with Platelet Activation

ISTH Academy, Faculty / Presenters, 407131

PB0742 JAK2 V617F Allele Burden and Thrombotic Events in Patients with JAK2 V617F Positive Polycythemia Vera or Essential Thrombocythemia at High Risk of Thrombosis

ISTH Academy, Faculty / Presenters, 407132

PB0738 Platelet Count and Its Correlation in Mutated Myeloid Neoplasm Patients; a Single Center Experience from Pakistan

ISTH Academy, Faculty / Presenters, 407133

PB0739 Study of a Low Anticoagulant Bovine Heparin as a Drug Capable of Disrupting Tumor Cell-Platelet Interaction and Preventing Hematogenous Metastasis

ISTH Academy, Faculty / Presenters, 407134

PB0735 Novel Synthetic Nilotinib Analogues with Improved Cytostatic Properties and Potent Antiplatelet Activity

ISTH Academy, Faculty / Presenters, 407135

PB0733 Patients with Pancreatic Cancer have a Disturbed Whole Blood Thrombin Generation Profile

ISTH Academy, Faculty / Presenters, 407136

PB0734 Platelet Procoagulant Potential Increases Following Thromboprophylaxis Completion in Patients with Primary Breast Cancer and Surgically Treated Metastatic Bone Disease

ISTH Academy, Faculty / Presenters, 407137

PB0731 Stabilized Platelets: A Drug Delivery System for Potential Human Hepatocellular Carcinoma Therapy

ISTH Academy, Faculty / Presenters, 407138

PB0748 Essential Oils of Colombian Plants Reduce Platelet Death and Spreading Area Induced by Dengue Virus and NS1-Protein

ISTH Academy, Faculty / Presenters, 407139

PB0749 Platelet Reactivity with Plasmodium Vivax Proteins

ISTH Academy, Faculty / Presenters, 407140

PB0747 Platelet Reactivity to Dengue and Zika Nonstructural Protein 1 (NS1)

ISTH Academy, Faculty / Presenters, 407141

PB0753 Circulating Levels of Podoplanin in Sickle Cell Disease

ISTH Academy, Faculty / Presenters, 407142

PB0754 Neutrophil Extracellular Traps as a Marker of Procoagulant State in Oncogynecological Patients

ISTH Academy, Faculty / Presenters, 407143

PB0751 Platelet Glycoprotein VI Drives Acute Pulmonary Inflammation by Promoting Neutrophil Recruitment, Clustering and NETosis

ISTH Academy, Faculty / Presenters, 407144

PB0752 Platelet Peptidylarginine Deiminase 4 is Not Essential for Platelet Activation or Development of Cardiac Fibrosis in Mice

ISTH Academy, Faculty / Presenters, 407145

PB0750 Platelets Promote Neutrophil Extracellular Traps Mediated Thrombo- Inflammation and Glomerular Endothelial Dysfunction in Diabetic Kidney Disease

ISTH Academy, Faculty / Presenters, 407146

PB0761 Autoantibodies Associated with Antiphospholipid Syndrome with Thrombotic Manifestations

ISTH Academy, Faculty / Presenters, 407147

PB0763 Sudden Bilateral Deafness Revealing Anti Phospholipid Syndrome

ISTH Academy, Faculty / Presenters, 407148

PB0760 Catastrophic Antiphospholipid Syndrome in Mexico

ISTH Academy, Faculty / Presenters, 407149

PB0758 Comparative study of Immunothrombotic Biomarkers in Patients with Rheumatologic Diseases and Long COVID

ISTH Academy, Faculty / Presenters, 407150

PB0759 Pulmonary Artery Thrombosis in Behçet's Syndrome: A Case Series

ISTH Academy, Faculty / Presenters, 407151

PB0757 Comparison of Clinical and Serological Features in Thrombotic Antiphospholipid Syndrome Patients, with and without Associated SLE, Followed for up to 42 Years: A Single Centre Retrospective Study

ISTH Academy, Faculty / Presenters, 407152

PB0764 Overwhelming Negative Impact of TET2 Mutations on Long-Term Survival After Transcatheter Aortic Valve Replacement

ISTH Academy, Faculty / Presenters, 407153

PB0766 Decreased Compactness and Increased Fluid Permeability of Ex-Vivo Fibrin Clots in Patients After Traumatic Brain Injury

ISTH Academy, Faculty / Presenters, 407154

PB0765 Increased Complement C3a Anaphylatoxin is Associated with Elevated Factor VIII and Altered Fibrin Clot Properties in Normotensive Patients with Acute Pulmonary Embolism

ISTH Academy, Faculty / Presenters, 407155

PB0768 Mouse Strain Specific Response to a Murine Coronavirus Respiratory Infection

ISTH Academy, Faculty / Presenters, 407156

PB0793 Establishing Reference Intervals of Coagulation Biomarkers in Human Immunodeficiency Virus Infection

ISTH Academy, Faculty / Presenters, 407157

PB0791 Bacterial Biofilms Produced by Staphylococcus sp. Act as Molecular Scaffolds for the Activation of Blood Coagulation

ISTH Academy, Faculty / Presenters, 407158

PB0792 Initiation of the Contact Activation System (CAS) and Complement System during Hemodialysis: A Prospective Observational Cohort Study

ISTH Academy, Faculty / Presenters, 407159

PB0790 Pediatric Swine Model of Escherichia coli Sepsis - Induced Disseminated Intravascular Coagulation (DIC) and Multiple Organ Dysfunction Syndrome (MODS)

ISTH Academy, Faculty / Presenters, 407160

PB0788 Serotonin Exhibits an Inhibitory Effect on NETosis

ISTH Academy, Faculty / Presenters, 407161

PB0785 NETosis and DNAses Exploration Development of an Assay to Explore Total DNAse Activity and Pre-Analytical Considerations for NETosis Markers et DNAses Activity

ISTH Academy, Faculty / Presenters, 407162

PB0787 Concordance of Low Molecular Weight and Unfractionated Heparin Serotonin Release Assays

ISTH Academy, Faculty / Presenters, 407163

PB0786 The Increased NETosis in Plasma of Patients with Periprosthetic Joint Infection is Aggravated by Lower DNaseI Activity: Potential Therapeutic Intervention to Eliminate the Bacterial Biofilm

ISTH Academy, Faculty / Presenters, 407164

PB0782 Monocyte-Dependent Antithrombotic Effect of Tranexamic Acid

ISTH Academy, Faculty / Presenters, 407165

PB0784 Endothelial P2X7 Promotes Venous Thromboembolism

ISTH Academy, Faculty / Presenters, 407166

PB0781 Involvement of Peptidylarginine Deiminase 4 in Eosinophil Extracellular Trap Formation and Contribution to Citrullinated Histone Signal in Thrombi

ISTH Academy, Faculty / Presenters, 407167

PB0779 NETs and Terminal Complement Pathway as Potential Biomarkers for Complement Overactivation Assessment in ANCA-Associated Vasculitis

ISTH Academy, Faculty / Presenters, 407168

PB0778 Impact of Biological Sex on the Host Response to Sepsis in PAD4- Deficient Mice

ISTH Academy, Faculty / Presenters, 407169

PB0780 Using Itga2b-creERT2 and Itga2b-creERT2-treml1 Transgenic Mice to Decipher TLT-1's Role in Platelet Interaction with Fibrinogen

ISTH Academy, Faculty / Presenters, 407170

PB0777 The Risk of Thrombosis in Patients with Acute Lymphoblastic Leukemia May Be Explained by the Impact of Peripheral Blasts on Endothelial Cells: An In-Vitro Study

ISTH Academy, Faculty / Presenters, 407171

PB0776 Characterization of the Effects of Hydroxyurea and Crizanlizumab on Plasma Immunothrombosis Biomarkers in Patients with Sickle Cell Disease

ISTH Academy, Faculty / Presenters, 407172

PB0775 Evaluation of Hemorrhage and Edema Expansion, Including Effecton Neutrophil-Mediated Neuroinflammation in Intracerebral Hemorrhage, Using Ir-CPI, a Thromboinflammation Inhibitor

ISTH Academy, Faculty / Presenters, 407173

PB0774 The Role of Immunothrombosis in Acute Coronary Syndrome (ACS) Patients during COVID-19 Pandemic: Analysis during a 2 Year Follow-Up

ISTH Academy, Faculty / Presenters, 407174

PB0772 Platelet-B Cell Interactions Modulate the Antibody Response to Adenoviral and mRNA Vaccines against SARS-CoV-2

ISTH Academy, Faculty / Presenters, 407175

PB0773 The RNA Aptamer, APTA-1 Targeting Evolutionarily Conserved Motif on Thrombin Cures Endotoxemia and Reduces Thrombosis in Animal Models by Inhibiting Aggregation and Secretion of Platelets

ISTH Academy, Faculty / Presenters, 407176

PB0770 Hyperinflammation and Extensive Cell Death Occurred in VITT and Indicate Severity and Poor Outcomes

ISTH Academy, Faculty / Presenters, 407177

PB0796 Interferon Treatment Suppresses in vitro NETosis in Neutrophils Derived from Patients with Myeloproliferative Neoplasms

ISTH Academy, Faculty / Presenters, 407178

PB0794 Fibrinogen Protects against Histone-Induced Thrombocytopaenia

ISTH Academy, Faculty / Presenters, 407179

PB0803 P2Y12 Receptor Expression on Monocytes, Monocyte-Derived Macrophages and Dendritic Cells and Modulation by Ticagrelor

ISTH Academy, Faculty / Presenters, 407180

PB0799 Extracellular Vesicles from Activated Platelets Possess a Shift in their Biochemical Profile and Enhance the Activity of the Prothrombinase Complex

ISTH Academy, Faculty / Presenters, 407181

PB0802 Platelet Features that Identify Early Stages of Liver Disease Progression

ISTH Academy, Faculty / Presenters, 407182

PB0800 Infection with Ancestral SARS-CoV-2 versus Variants of Concern Delta and Omicron Differentially Alter the Megakaryocyte Transcriptome

ISTH Academy, Faculty / Presenters, 407183

PB0801 Influence of IL-6 Classical and Trans-Signaling on Platelet Activation

ISTH Academy, Faculty / Presenters, 407184

PB0797 Comparison of Platelet Activation between Established and Novel FCγRIIA Ligands

ISTH Academy, Faculty / Presenters, 407185

PB0798 Role of Platelets in Maintain Lung Hemostasis during dsRNA-Induced Acute Respiratory Distress Syndrome (ARDS) in Mice

ISTH Academy, Faculty / Presenters, 407186

PB0249 Some Coagulation Profiles (PT, APTT, TT, FIB), Red Cell, Total White Cell, Platelet Counts and Their Indices Activity Levels in Persons Exposed to Wood Smoke (Firewood) in Calabar, Nigeria

ISTH Academy, Faculty / Presenters, 407187

PB0248 Changes in Some Coagulation Parameters of Single Women Using Some Oral and Injectable Contraceptives in Calabar Metropolis, Cross River, Nigeria

ISTH Academy, Faculty / Presenters, 407188

PB0244 Analysis of Drug Related Problem Associated with Direct Oral Anticoagulants: Findings from a Medical Records Review by Pharmacists in a Large Teaching Hospital

ISTH Academy, Faculty / Presenters, 407189

PB0245 Equitable Care for Individuals with Inherited Bleeding and Substance Use Disorders

ISTH Academy, Faculty / Presenters, 407190

PB0243 Trends in Vitamin K Antagonist Use Indicate Prescription Patterns That May Be Over-Utilizing Direct Oral Anticoagulants without Adequate Gains in Side Effect Profile or Improved Cost-Effectiveness

ISTH Academy, Faculty / Presenters, 407191

PB0246 FXIII Deficiency: A Genetic Diagnostic Dilemma

ISTH Academy, Faculty / Presenters, 407192

PB0272 Hypofibrinogenemia and Liver Disease: First Report in a Family of Greek Origin

ISTH Academy, Faculty / Presenters, 407193

PB0271 Acquired Factor XI Deficiency in a Child with Membranous Glomerulonephritis

ISTH Academy, Faculty / Presenters, 407194

PB0270 Management of Dysfibrinogenemia in a Pediatric Patient Undergoing Scoliosis Repair: Case Report

ISTH Academy, Faculty / Presenters, 407195

PB0268 Desmopressin Response May Fail in Children with Congenital Platelet Function Defects

ISTH Academy, Faculty / Presenters, 407196

PB0269 Health-Related Quality of Life of, and Burden of Caring for, Thai Patients with Hemophilia Using the Canadian Hemophilia Outcomes-Kids' Life Assessment Tool v3.0 and Hemophilia Family Impact Tool

ISTH Academy, Faculty / Presenters, 407197

PB0267 High-Dose Dexamethasone Corrects the Elevated TCRαβ+ Double-Negative T Cells in Pediatric Patients with Primary Immune Thrombocytopenia

ISTH Academy, Faculty / Presenters, 407198

PB0266 Effect of COVID-19 Vaccine or Infection on Pediatric Patients with Current or Prior Immune Thrombocytopenia

ISTH Academy, Faculty / Presenters, 407199

PB0263 ISTH DIC and SIC Score are Associated with Early Mortality in Children with Sepsis Induced Disseminated Intravascular Coagulation

ISTH Academy, Faculty / Presenters, 407200

PB0264 Validation of the English Adolescent Menstrual Poverty Questionnaire (aMPQ)

ISTH Academy, Faculty / Presenters, 407201

PB0265 WeThrive App Improves Adolescents' Understanding of Menses

ISTH Academy, Faculty / Presenters, 407202

PB0259 Diagnostic Utility of Full Blood Count Screening in Neonates Born to Mothers with Moderate-Severe Thrombocytopenia

ISTH Academy, Faculty / Presenters, 407203

PB0260 Immune Complex-Mediated Acquired von Willebrand Syndrome in a 5-year-old Boy after Allogeneic Hematopoietic Stem Cell Transplantation

ISTH Academy, Faculty / Presenters, 407204

PB0261 Prediction of Favorable Outcome and Quality of Life of Children Diagnosed with Immune Thrombocytopenia

ISTH Academy, Faculty / Presenters, 407205

PB0258 Haemostasis Derangements in Neonates with Hypoxic Ischemic Encephalopathy (HIE) Compared with Term Neonates by Using Rotational Thromboelastometry (ROTEM)

ISTH Academy, Faculty / Presenters, 407206

PB0257 Adequate Menstrual Suppression in Adolescents with Bleeding Disorders Often Requires Multiple Treatment Changes: Five-Year Experience of a Large Multidisciplinary Clinic

ISTH Academy, Faculty / Presenters, 407207

PB0255 Relationship between Serum TPO Levels and Proportions of T cell Subsets in Children with Immune Thrombocytopenia

ISTH Academy, Faculty / Presenters, 407208

PB0254 Factor XI and XII in Children Undergoing Extracorporeal Membrane Oxygenation (ECMO)

ISTH Academy, Faculty / Presenters, 407209

PB0252 The Role of Hydroxychloroquine in the Management of Children with ITP and Positive Antinuclear Antibodies

ISTH Academy, Faculty / Presenters, 407210

PB0250 Prevalence of Iron Deficiency in Patients with Inherited Bleeding Disorders

ISTH Academy, Faculty / Presenters, 407211

PB0251 The Impact of Switching from Intravenous Recombinant Factor VIII Concentrate to a Non-Factor Concentrate on Health-Related Quality of Life in Boys with Hemophilia A

ISTH Academy, Faculty / Presenters, 407212

PB0311 Anticoagulation in a Hypercoagulable Infant with End-Stage Renal Disease on Renal Replacement Therapies

ISTH Academy, Faculty / Presenters, 407213

PB0310 Arterial Ischemic Stroke Related to Minor Head Trauma: A Report of Five Pediatric Cases

ISTH Academy, Faculty / Presenters, 407214

PB0309 Safety and Efficacy of Apixaban Therapy in an Obese Adolescent with Pulmonary Embolism

ISTH Academy, Faculty / Presenters, 407215

PB0308 Anticoagulation Monitoring of UFH (Unfractioned Heparin) in a Pediatric Patient during Long Term ECMO (Extracorporeal Membrane Oxygenation)

ISTH Academy, Faculty / Presenters, 407216

PB0307 Pediatric Pulmonary Embolism and Pulmonary Hypertension Associated with E-Cigarette use

ISTH Academy, Faculty / Presenters, 407217

PB0306 Thromboprophylaxis in Pediatric Patient with Acute Lymphoblastic Leukemia and Treatment with Asparaginase

ISTH Academy, Faculty / Presenters, 407218

PB0304 Bivalirudin Anticoagulation for an Infant with Heparin Resistance on ECMO

ISTH Academy, Faculty / Presenters, 407219

PB0300 Diagnosis of Thromboembolism in Children with Cancer: Validation of Diagnostic Algorithms Using Real-World Data

ISTH Academy, Faculty / Presenters, 407220

PB0301 Ocular Vein Occlusion in Pediatrics: Should Thrombophilia Investigation and Anticoagulant Treatment be Initiated?

ISTH Academy, Faculty / Presenters, 407221

PB0302 Preventing Thrombosis in Moderate-Severe Protein C Deficiency: The Effects of Different Treatment Regimensin a Boywith Protein C Level of 4 IU/dl

ISTH Academy, Faculty / Presenters, 407222

PB0297 Antiphosphatidylserine/Prothrombin Antibodies in Childhood SLE are Associated with Lupus Anticoagulant Positivity

ISTH Academy, Faculty / Presenters, 407223

PB0298 Catheter-Directed Thrombolysis and Systemic Anticoagulation for IVC and Bilateral Renal Vein Thrombosis in a Septic Neonate

ISTH Academy, Faculty / Presenters, 407224

PB0299 Surface Modification of Lung Assist Device for Neonates by Dual-Modification with Antithrombin-Heparin (ATH) and Tissue Plasminogen Activator (t-PA)

ISTH Academy, Faculty / Presenters, 407225

PB0293 Development of a Pediatric Pulmonary Embolism Response Team: An Institutional Experience

ISTH Academy, Faculty / Presenters, 407226

PB0294 Incidence of Venous Thromboembolism (VTE) in Adventh-Pediatric Registry in a Southeastern Brazilian City

ISTH Academy, Faculty / Presenters, 407227

PB0295 Off-Label Use of Rivaroxaban in the Management of Three Cases of Pediatric Arterial Ischemic Stroke

ISTH Academy, Faculty / Presenters, 407228

PB0288 Antiphospholipid Syndrome in Children: 30 Years Single-Center Prospective Pediatric Cohort from Argentina

ISTH Academy, Faculty / Presenters, 407229