Rivaroxaban and apixaban induce clotting factor Xa fibrinolytic activity

ISTH Academy, Ed Pryzdial, 273301

The mitochondrial calcium uniporter regulates procoagulant platelet formation

ISTH Academy, Shawn M. Jobe, 273302

Is there a role for von Willebrand factor/factor VIII concentrate supplementation in complex congenital heart surgery?

ISTH Academy, Marco Ranucci, 273303

Protein disulfide isomerase regulation by nitric oxide maintains vascular quiescence and controls thrombus formation

ISTH Academy, Christophe Dubois, 273304

The utility of viscoelastic methods in the prevention and treatment of bleeding and hospital‐associated venous thromboembolism in perioperative care: guidance from the SSC of the ISTH

ISTH Academy, Beverley Hunt, 273305

What the neighbors say

ISTH Academy, Session Speakers, 273306

Hereditary angioedema: the plasma contact system out of control: reply

ISTH Academy, Coen Maas, 273316

Elimination of factor VIII‐specific B cells by immunotoxins composed of a single factor VIII domain fused to Pseudomonas exotoxin A

ISTH Academy, Christoph Königs, 273317

Acquired von Willebrand syndrome in congenital heart disease surgery: results from an observational case‐series

ISTH Academy, Vanya Icheva, 273318

Heparin‐induced thrombocytopenia‐associated thrombosis: from arterial to venous to venous limb gangrene

ISTH Academy, Theodore Earl Warkentin, 273319

Repeated assessments of physical activity and risk of incident venous thromboembolism

ISTH Academy, Line H. Evensen, 273320

Hereditary angioedema: the plasma contact system out of control: comment

ISTH Academy, M. Triggiani, 273321

Marc Verstraete (1925–2018)

ISTH Academy, Session Speakers, 273322

Module 2: Primary Immune Thrombocytopenia

ISTH Academy, Dr. Siraj Mithoowani, Dr. Cindy Neunert & Dr. Donald Arnold, 234315

Module 3: Heparin-Induced Thrombocytopenia

ISTH Academy, Prof. François Mullier, Dr. Geoffrey Horlait, Dr. Isabelle Michaux, Prof. Claire Pouplard & Prof. Yves Gruel, 234314

Archived Webinar: Considering Patient Profile in VTE Extended Anticoagulation: Applying Evidence to Clinical Practice

ISTH Academy, Scott Stevens & Gregory Piazza, 223425

Diagnose and manage patients with immune thrombocytopenia (ITP) applying indications for treatment and treatment options

ISTH Academy, ISTH, 120241

Relate the principles of the structural and functional aspects of the biology of factor VIII (FVIII) and factor IX (FIX) to clinical management of patients with haemophilia A or B

ISTH Academy, ISTH, 120250

Recognize clinical manifestations of haemophilia

ISTH Academy, ISTH, 120251

Diagnose haemophilia A and B by interpreting laboratory tests

ISTH Academy, ISTH, 120252

Perform laboratory tests for diagnosis of haemophilia A and B

ISTH Academy, ISTH, 120253

Relate the principles of the epidemiology, immunology and molecular basis of inhibitors to FVIII, or FIX to clinical management of patients with haemophilia A or B

ISTH Academy, ISTH, 120255

Diagnose patients with inhibitors to FVIII and FIX by interpreting laboratory tests

ISTH Academy, ISTH, 120256

Manage dosing regimens for immune tolerance induction in patients with inhibitors, as well as in the use of immunosuppressive drugs, apheresis and immunoadsorption

ISTH Academy, ISTH, 120259

Provide management plans for physiotherapists for prevention and treatment of arthropathy in haemophilia patients

ISTH Academy, ISTH, 120262

Provide advice for management of haemostasis in symptomatic carriers of haemophilia A and B requiring surgery

ISTH Academy, ISTH, 120263

Appreciate the issues relating to the provision of haemophilia care in different parts of the world and the difficulties of providing diagnostic and therapeutic services in some countries

ISTH Academy, ISTH, 120266

Diagnose and classify VWD by interpretation of laboratory tests

ISTH Academy, ISTH, 120271

Perform laboratory tests for diagnosis and classification of VWD

ISTH Academy, ISTH, 120272

Develop clinical management plans for patients with VWD

ISTH Academy, ISTH, 120273

Manage treatment of bleeds in patients with VWD, including use of desmopressin acetate, FVIII/VWF concentrates, cryoprecipitate, antifibrinolytics and fibrin glue

ISTH Academy, ISTH, 120274

Diagnose and treat patients with VWD and inhibitors

ISTH Academy, ISTH, 120275

Diagnose and manage patients with superficial venous thrombosis

ISTH Academy, ISTH, 120298

Diagnose and manage patients with thrombosis due to antiphospholipid syndrome

ISTH Academy, ISTH, 120299

Develop and apply recommendations for thromboprophylaxis, including mechanical and pharmacological interventions, in patients at risk of venous thromboembolism e.g. peri-operative and post-traumatic period, and other periods of immobility

ISTH Academy, ISTH, 120303

Investigate women for relevant haemostatic factors involved in placenta-mediated pregnancy complications (preeclampsia, fetal loss, stillbirth, placental abruption)

ISTH Academy, ISTH, 120325

Assess and manage gynaecological and obstetric issues in women with inherited bleeding disorders

ISTH Academy, ISTH, 120328

Manage haematological aspects of postpartum haemorrhage

ISTH Academy, ISTH, 120329

The Burden of Hospital-Associated VTE: Facts Every Clinician Should Know

ISTH Academy, ISTH Academy, 227662

Preventing Thrombosis During and Post-Hospitalization: New Paradigms in Clinical Care

ISTH Academy, ISTH Academy, 227661

Ranking the stars

ISTH Academy, Session Speakers, 234149

Factor XI promotes hemostasis in factor IX‐deficient mice

ISTH Academy, David Gailani, 234150

The next best thing in factor VIIa

ISTH Academy, Maureane Hoffman, 234151

Genome‐wide analysis of genetic determinants of circulating factor VII‐activating protease (FSAP) activity

ISTH Academy, Maja Olsson, 234152

The American College of Chest Physician score to assess the risk of bleeding during anticoagulation in patients with venous thromboembolism

ISTH Academy, Gualtiero Palareti, 234153

Nano‐evidence for joint microbleeds in hemophilia patients

ISTH Academy, John Puetz, 234154

The predictive value of factor VIII/factor IX levels to define the severity of hemophilia: communication from the SSC of ISTH

ISTH Academy, Alberto Tosetto, 234155

Mortality due to bleeding, myocardial infarction and stroke in dialysis patients

ISTH Academy, G. Ocak, 234156

Laboratory criteria for antiphospholipid syndrome: reply

ISTH Academy, Katrien Devreese, 234157

Stay Coagulated and Join the ISTH Today

ISTH Academy, Session Speakers, 234158

Use of factor concentrates for the management of perioperative bleeding: reply

ISTH Academy, Anne Godier, 234159

Longitudinal increases in blood biomarkers of inflammation or cardiovascular disease and the incidence of venous thromboembolism

ISTH Academy, Aaron R. Folsom, 234160

Laboratory criteria for antiphospholipid syndrome: comment

ISTH Academy, Karl Lackner, 234161

Local chromatin interactions contribute to expression of the fibrinogen gene cluster

ISTH Academy, Marguerite Neerman-Arbez, 234162

Cerebral venous sinus thrombosis

ISTH Academy, Ida Martinelli, 234163

Heparin–protamine balance after neonatal cardiopulmonary bypass surgery

ISTH Academy, Alan Mast, 234164

Small molecule targeting the Rac1‐NOX2 interaction prevents collagen‐related peptide and thrombin‐induced reactive oxygen species generation and platelet activation

ISTH Academy, Huzoor Akbar, 234165

What the neighbors say

ISTH Academy, Session Speakers, 234166

The chaperone‐like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation

ISTH Academy, Alessio Branchini, 234167

Identification of high thrombotic risk triple‐positive antiphospholipid syndrome patients is dependent on anti‐cardiolipin and anti‐β2glycoprotein I antibody detection assays

ISTH Academy, Katrien Devreese, 234168

Issue Information

ISTH Academy, Session Speakers, 234169

Delimiting the autoinhibitory module of von Willebrand factor

ISTH Academy, Wei Deng, 234170

Tissue factor at the crossroad of coagulation and cell signaling

ISTH Academy, Wolfram Ruf, 234171

Phase 1, single‐dose escalating study of marzeptacog alfa (activated), a recombinant factor VIIa variant, in patients with severe hemophilia

ISTH Academy, Ralph A. Gruppo, 234172

Weight‐adjusted tinzaparin for the prevention of venous thromboembolism after bariatric surgery

ISTH Academy, Deborah Siegal, 234173

Use of factor concentrates for the management of perioperative bleeding: comment

ISTH Academy, Nigel Sargant, 234174

Venous thromboembolism in patients with liver diseases

ISTH Academy, Raquel Barba, 234175

Fibrinolysis: strategies to enhance the treatment of acute ischemic stroke

ISTH Academy, Paul Y. Kim, 234176

Carboxypeptidase U (CPU, carboxypeptidase B2, activated thrombin‐activatable fibrinolysis inhibitor) inhibition stimulates the fibrinolytic rate in different in vitro models

ISTH Academy, D. Hendriks, 234177

Assessment of whole blood coagulation with a microfluidic dielectric sensor

ISTH Academy, Pedram Mohseni, 234178

Pediatric Thrombosis

ISTH Academy, Mary Bauman & Sophie Jones, 223426

Perioperative Management of Patients who are Receiving Anticoagulant Therapy

ISTH Academy, James Douketis & Deborah Siegal, 228093

Module 1: Mechanisms of Platelet Production and Destruction

ISTH Academy, Prof. Tamam Bakchoul, Dr. Ishac Nazy & Dr. Shinji Kunishima, 228094

Targeting platelet EPCR for better therapeutic factor VIIa activity

ISTH Academy, Steven Lentz, 230955

Mechanisms and mitigating factors for venous thromboembolism in chronic kidney disease: the REGARDS study

ISTH Academy, Katharine L. Cheung, 230956

Risk factors for bleeding, including platelet count threshold, in newly diagnosed immune thrombocytopenia adults

ISTH Academy, Guillaume Moulis, 230957

Flavin monooxygenase 3, the host hepatic enzyme in the metaorganismal trimethylamine N‐oxide‐generating pathway, modulates platelet responsiveness and thrombosis risk

ISTH Academy, Stanley L. Hazen, 230958

PDK1 governs thromboxane generation and thrombosis in platelets by regulating activation of Raf1 in the MAPK pathway: reply

ISTH Academy, Matthew Rondina, 230960

Acquired platelet antagonism: off‐target antiplatelet effects of malignancy treatment with tyrosine kinase inhibitors

ISTH Academy, Marijke Kuijpers, 230961

What the neighbors say

ISTH Academy, Session Speakers, 230962

A first‐in‐human study of the safety, tolerability, pharmacokinetics and pharmacodynamics of PF‐06741086, an anti‐tissue factor pathway inhibitor mAb, in healthy volunteers

ISTH Academy, Matthew Cardinal, 230963

Discovery of novel plasma biomarkers for future incident venous thromboembolism by untargeted synchronous precursor selection mass spectrometry proteomics

ISTH Academy, Søren Beck Jensen, 230964

Human platelets express endothelial protein C receptor, which can be utilized to enhance localization of factor VIIa activity

ISTH Academy, Ammon M. Fager, 230965

Substantial recurrence risk after venous thromboembolism provoked by minor risk factors

ISTH Academy, Sigrid Braekkan, 230966

Issue Information

ISTH Academy, Session Speakers, 230967

Thrombopoietin receptor agonists in hereditary thrombocytopenias

ISTH Academy, Francesco Rodeghiero, 230968

Diagnosis and classification of congenital fibrinogen disorders: communication from the SSC of the ISTH

ISTH Academy, Alessandro Casini, 230969

Less abnormal uterine bleeding with dabigatran than warfarin in women treated for acute venous thromboembolism

ISTH Academy, Menno Huisman, 230970

Stay Coagulated and Join the ISTH Today

ISTH Academy, Session Speakers, 230971

Autoantibody against integrin αβ contributes to thrombocytopenia by blocking the migration and adhesion of megakaryocytes

ISTH Academy, Junping Wang, 230972

Tuning the endothelial response: differential release of exocytic cargos from Weibel‐Palade bodies

ISTH Academy, Daniel Cutler, 230973

Chemical and pharmacological aspects of neutralization of heparins from different animal sources by protamine

ISTH Academy, Paulo A. S. Mourão, 230974

Learning by counting blood platelets in population studies: survey and perspective a long way after Bizzozero

ISTH Academy, Chiara Cerletti, 230976

Predators

ISTH Academy, Session Speakers, 230977

The pediatric acenocoumarol dosing algorithm: the Children Anticoagulation and Pharmacogenetics Study

ISTH Academy, Anthonius de Boer, 230978

PDK1 governs thromboxane generation and thrombosis in platelets by regulating activation of Raf1 in the MAPK pathway: comment

ISTH Academy, Ulhas Naik, 230979

Hereditary angioedema: the plasma contact system out of control

ISTH Academy, Coen Maas, 230980

Anti‐C1 domain antibodies that accelerate factor VIII clearance contribute to antibody pathogenicity in a murine hemophilia A model

ISTH Academy, Shannon L. Meeks, 230981

Role of direct oral anticoagulants in the treatment of cancer‐associated venous thromboembolism: guidance from the SSC of the ISTH

ISTH Academy, Alok Khorana, 230982

The use of platelets in regenerative medicine and proposal for a new classification system: guidance from the SSC of the ISTH

ISTH Academy, Paul Harrison, 230983