OC 01.4 Prevalence of Chronic Thromboembolic Pulmonary Hypertension and Evaluation of Thrombus Resolution in COVID-19-Associated Pulmonary Embolism Survivors

ISTH Academy, Faculty / Presenters, 406433

OC 34.2 Chronic Inflammatory Diseases Increase the Risk of Post-Thrombotic Syndrome: a Prospective Cohort Study

ISTH Academy, Faculty / Presenters, 406434

OC 09.2 Biomechanics, Energetics, and Structural Basis of Rupture of Fibrin Networks with Varying Density

ISTH Academy, Faculty / Presenters, 406435

OC 17.3 Prothrombotic Polymorphisms FV Leiden and Prothrombin G20210A in 699 Unrelated Patients with Congenital Antithrombin Deficiency: More than a Prognostic Value

ISTH Academy, Faculty / Presenters, 406436

OC 01.1 Discordance between Computed Tomography Pulmonary Angiography (CTPA) and Transthoracic Echocardiography (TTE) in Identification of Right Ventricular Strain in Patients with Acute Pulmonary Embolism

ISTH Academy, Faculty / Presenters, 406437

OC 72.5 Prediction of Venous Thromboembolism in Diverse Ancestry Populations Using Machine Learning and Electronic Health Records

ISTH Academy, Faculty / Presenters, 406438

OC 11.2 Pulmonary Embolism Diagnostic Strategies in Patients with COPD Exacerbation: Post-Hoc Analysis of the Pep Trial

ISTH Academy, Faculty / Presenters, 406439

OC 11.1 Development and Validation of a Clinical Prediction Model for the Diagnostic Management of Acute Pulmonary Embolism: An Individual Participant Data Meta-Analysis

ISTH Academy, Faculty / Presenters, 406440

OC 11.5 Diagnostic Strategies in Patients on Anticoagulation Presenting with a Suspicion of Recurrent Venous Thromboembolism

ISTH Academy, Faculty / Presenters, 406441

OC 11.3 Association between Body Mass Index and Pulmonary Embolism and Performance of the Age-Adjusted D-dimer Strategy in Obese Patients with Suspected Pulmonary Embolism: A Prospective Management Study

ISTH Academy, Faculty / Presenters, 406442

OC 11.4 Diagnosis of Deep Vein Thrombosis Using a D-Dimer Threshold Adjusted to Clinical Probability: Supportive Real-World Evidence for a Change in Clinical Practice

ISTH Academy, Faculty / Presenters, 406443

OC 40.3 High-Sensitivity Versus Conventional Troponin Cutoffs for Risk Stratification in Patients with Hemodynamically-Stable Acute Pulmonary Embolism

ISTH Academy, Faculty / Presenters, 406444

OC 63.4 Prevalence of Pulmonary Embolism in Patients with Chronic Obstructive Pulmonary Disease Exacerbation in North America – A Single Center Experience

ISTH Academy, Faculty / Presenters, 406445

OC 63.5 A Neural Network Approach to Predict Recurrent VTE Based on Coagulation Parameters

ISTH Academy, Faculty / Presenters, 406446

OC 72.2 Prevalence and Survival of Out-of-Hospital Cardiac Arrest Associated with Venous Thromboembolism – ASwedish Population-Based Cohort Study

ISTH Academy, Faculty / Presenters, 406447

OC 63.3 Combined Effect of High Factor VIII Levels and High Mean Platelet Volume on the Risk of Future Venous Thromboembolism

ISTH Academy, Faculty / Presenters, 406448

OC 21.1 Venous Thromboembolism and Vascular Access Thrombosis in Patients with End-Stage Kidney Disease on Hemodialysis: Prospective Results from the VIVALDI Study

ISTH Academy, Faculty / Presenters, 406449

OC 72.3 Risk of Pulmonary Embolism and Deep Vein Thrombosis Associated with Short-Term Air Pollution

ISTH Academy, Faculty / Presenters, 406450

OC 72.1 Knowledge of Venous Thromboembolism Among Nigeria Pregnant Women: A Preliminary Survey for the ‘Move for Flow’ Program

ISTH Academy, Faculty / Presenters, 406451

OC 63.2 Plasma Expression Levels of microRNA-145 are Associated with Risk of Future Venous Thromboembolism

ISTH Academy, Faculty / Presenters, 406452

OC 32.1 Risk Factors for Venous Thrombosis after Discharge from Medical Hospitalizations: The Medical Inpatient Thrombosis and Hemostasis (MITH) Study

ISTH Academy, Faculty / Presenters, 406453

OC 63.1 The Plasma Proteome and Risk of Venous Thromboembolism (VTE)

ISTH Academy, Faculty / Presenters, 406454

OC 72.4 Risk of Venous Thromboembolism (VTE) in First-Degree Relatives of Patients with VTE Compared with General Population VTE Risk

ISTH Academy, Faculty / Presenters, 406455

PB0579 Approaches to Assure Similarity of Pharmaceutical Preparations of Unfractionated Heparin

ISTH Academy, Faculty / Presenters, 406544

PB0580 Laboratory Diagnosis of Prekallikrein Deficiency: Importance of Suspicion and Laboratory Method

ISTH Academy, Faculty / Presenters, 406545

PB0576 Correlation between High Affinity Material for Antithrombin and Anticoagulant Activities of Heparin

ISTH Academy, Faculty / Presenters, 406546

PB0577 Heparin Potency Assays – Reagents can Cause Differences in Potency Assignment

ISTH Academy, Faculty / Presenters, 406547

PB0575 Novel Variants of PROS1 Gene Related to Protein S Deficiency

ISTH Academy, Faculty / Presenters, 406548

PB0570 A Comparison of Heparins from Porcine and Bovine Origins in Various Laboratory Assays

ISTH Academy, Faculty / Presenters, 406549

PB0571 Analysis of the Risk Factors on the Development of Thromboembolic Complications

ISTH Academy, Faculty / Presenters, 406550

PB0572 Potency-Adjusted Bovine Heparin Exhibits Similar Anticoagulant Effects as Porcine Heparin in Whole Blood Clotting Studies

ISTH Academy, Faculty / Presenters, 406551

PB0573 Routine Haemostasis Profile in Sickle Cell Disease Patients in Steady State: A Retrospective, Descriptive Study

ISTH Academy, Faculty / Presenters, 406552

PB0574 Severe Bleeding in an Acquired Factor XIII Deficiency in an Otherwise Healthy Patient

ISTH Academy, Faculty / Presenters, 406553

PB0569 Elevated International Normalized Ratio in Hospitalized Patients Treated with Direct Oral Anticoagulants

ISTH Academy, Faculty / Presenters, 406554

PB0562 Effects of High-Fat and High-Carbohydrate Meals on Coagulation and Anticoagulation Factors and Lipid Profile

ISTH Academy, Faculty / Presenters, 406555

PB0563 Evaluation of the Rapid and Easy-to-Use Point-of-Care qLabs FIB® System to Quantify Functional Fibrinogen Levels in Patients Undergoing Plasma Exchange Therapy

ISTH Academy, Faculty / Presenters, 406556

PB0564 Evaluation of the Significance of Mixing Study in Lupus Anticoagulant Testing Using A New CMC Algorithm

ISTH Academy, Faculty / Presenters, 406557

PB0565 Long-Term ex-situ Normothermic Machine Perfusion of Human Livers Provides a Platform to Study (Patho)Physiology and Production of Hemostatic Proteins

ISTH Academy, Faculty / Presenters, 406558

PB0566 Prediction and Validation of the Effects of Targeting either Coagulation FXI Activation or Activity on Thrombin Generation

ISTH Academy, Faculty / Presenters, 406559

PB0568 X-Ray Structures of Thrombin Bound to Heterobifunctional Aptamer-Drug Conjugates Reveal the Mechanistic Basis for a Novel Tethered Inhibition Strategy

ISTH Academy, Faculty / Presenters, 406560

PB0554 A Phase 1/2 Study to Determine the Dose-Response Relationship by Assessment of Thrombin Generation After 4-Factor PCC in Healthy Subjects under Vitamin K Antagonist Anticoagulation

ISTH Academy, Faculty / Presenters, 406561

PB0555 Efficacy and Safety of 4-Factor Prothrombin Complex Concentrate for Management for Direct Xa Inhibitor-Induced Major Bleeding

ISTH Academy, Faculty / Presenters, 406562

PB0556 Evaluation of the ACL TOP 970 CL Analyser for Clotting, Chromogenic and Immunoturbidimetric Assays for Thrombophilia

ISTH Academy, Faculty / Presenters, 406563

PB0557 Fermentation of Sweet Corn Produced a Very High Concentration of Vitamin K

ISTH Academy, Faculty / Presenters, 406564

PB0558 Lack of Interaction of Milvexian, an Investigational Oral FXIa Inhibitor with Aspirin and Ticagrelor on Platelet Aggregation, Thrombin Generation and Thromboelastography in vitro

ISTH Academy, Faculty / Presenters, 406565

PB0559 Novel Variants of PROS1 Gene Related to Protein S Deficiency

ISTH Academy, Faculty / Presenters, 406566

PB0560 Step-by-Step Production and Biological Evaluation of Novel Aryl Piperazine-based FXa Inhibitors

ISTH Academy, Faculty / Presenters, 406567

PB0551 A Comparison of USP Potency Adjusted and Mass Adjusted Heparins of Bovine, Ovine, and Porcine Origin in Various Assays

ISTH Academy, Faculty / Presenters, 406568

PB0552 Performance Evaluation of the ACTICHROME Heparin Anti-Xa Assay for the Quantitative Determination of Unfractionated Heparin and Low-Molecular-Weight Heparin Plasma Concentrations

ISTH Academy, Faculty / Presenters, 406569

PB0553 Role of International Society of Thrombosis and Hemostasis-Bleeding Assessment Tool, RICOF, ROTEM, and APTT-Clot wave form Analysis (CWA) in Evaluation of Patients with Bleeding of Unknown Cause (BUC)

ISTH Academy, Faculty / Presenters, 406570

PB0548 Efficacy of Direct Oral Anticoagulants in Liver Cirrhosis: An in-vitro Study

ISTH Academy, Faculty / Presenters, 406571

PB0549 Healthcare Resource Use Among US Veterans Treated with Andexanet Alfa or 4-Factor Prothrombin Complex Concentrate for Factor Xa Inhibitor-Related Major Bleeding

ISTH Academy, Faculty / Presenters, 406572

PB0550 Novel Variants of PROS1 Gene Related to Protein S Deficiency

ISTH Academy, Faculty / Presenters, 406573

PB0546 Effect of Atorvastatin on IL-6 and F1+2 in High Risk Thrombosis Patients with Cancer Undergoing Chemotherapy

ISTH Academy, Faculty / Presenters, 406574

PB0547 Poly(Sodium Styrenesulfonate)-based Copolymers with Anticoagulant Activity: Preliminary Efficacy and Safety Studies

ISTH Academy, Faculty / Presenters, 406575

PB0538 A Monoclonal Antibody against Human Factor V Impairs its Activation and Procoagulant Function

ISTH Academy, Faculty / Presenters, 406576

PB0539 Detection of TFPI Citrullination in Blood after Neutrophil Activation by PMA

ISTH Academy, Faculty / Presenters, 406577

PB0541 Expression of Recombinant Human Factor VII Activating Protease (FSAP) and Exploration of its 3D Structure Using AlphaFold

ISTH Academy, Faculty / Presenters, 406578

PB0542 Investigating Thrombin-Loaded Fibrin in Whole Blood Clot Microfluidic Assay via Fluorogenic Peptide

ISTH Academy, Faculty / Presenters, 406579

PB0543 Like Heparin, Polyphosphate Promotes the Formation of a Ternary Complex with Thrombin and Fibrin

ISTH Academy, Faculty / Presenters, 406580

PB0544 Management of Inherited Antithrombin Deficiency in Pregnancy and Puerperium: Single Center Experience

ISTH Academy, Faculty / Presenters, 406581

PB0545 The Effect of a History of Preeclampsia on Hemostatic Balance in the Non-Pregnant State

ISTH Academy, Faculty / Presenters, 406582

PB0535 Development of Function-Blocking Antibodies to Plasma Prekallikrein for the Study of the Interplay between Coagulation and Inflammation

ISTH Academy, Faculty / Presenters, 406583

PB0536 Oral Factor XIIa Inhibitor KV998086 Protects Against FeCl3 Induced Thrombosis in Mice

ISTH Academy, Faculty / Presenters, 406584

PB0537 Tissue Factor Pathway Inhibitor and Tissue Factor Pathway Inhibitorrs7586970 Variant in Myocardial Infarction with Type 2 Diabetes Mellitus

ISTH Academy, Faculty / Presenters, 406585

PB0533 New Low Molecular Weight Heparin Antidote Based on an Antithrombin Mutant

ISTH Academy, Faculty / Presenters, 406586

PB0534 Rapid Measurement of DOAC Concentration and Platelet Function Using Whole Blood in a Disposable Microfluidic Device

ISTH Academy, Faculty / Presenters, 406587

PB0531 Mechanical Behavior of Clots: Molecular Mechanism of Forced Unfolding of Crosslinked Fibrin Protofibrils

ISTH Academy, Faculty / Presenters, 406588

PB0532 The Factor XIa Antibody Osocimab Combined with Enoxaparin Strongly Inhibits Clotting in Extracorporeal Circuits in vitro

ISTH Academy, Faculty / Presenters, 406589

PB0530 Sex-Specific Differences in Procoagulant Profiles

ISTH Academy, Faculty / Presenters, 406590

PB0598 Blood Anticoagulant Impacts Endogenous Thrombin Generation in a Peripartum Population

ISTH Academy, Faculty / Presenters, 406591

PB0596 Characterization of Anti-Polyphosphate Monoclonal Antibodies

ISTH Academy, Faculty / Presenters, 406592

PB0597 Specificity of Contact Pathway Inhibitors with Regard to Other Coagulation and Fibrinolysis Proteases

ISTH Academy, Faculty / Presenters, 406593

PB0593 Extending the Circulatory Half-Life of an Engineered Kallikrein-Specific Inhibitor

ISTH Academy, Faculty / Presenters, 406594

PB0594 Factor XI Localization in Human Deep Venous Thrombus and Function of Activated Factor XI on Mural Thrombus Formation Under Low-Shear Condition

ISTH Academy, Faculty / Presenters, 406595

PB0591 Alphafold AI based Applications Explored as Tools for Predicting Contact Proteins PK, FXI and HK Structure and Evolutionary Relationships

ISTH Academy, Faculty / Presenters, 406596

PB0595 The Profile of Contact Activation System Proteins in Human Abdominal Aortic Aneurysm Plasma-and Tissue Samples

ISTH Academy, Faculty / Presenters, 406597

PB0592 Evaluation of the Role of Skeletal Muscle Myosin as a Cofactor for Factor XI Activation of Factor XII

ISTH Academy, Faculty / Presenters, 406598

PB0588 Epitope Mapping of the α-FXIIa Allosteric Inhibitor Monoclonal Antibody 5C12

ISTH Academy, Faculty / Presenters, 406599

PB0589 Human Transthyretin (hTTR) Amyloid Fibrils Induce Plasma Clotting by Activating the Intrinsic Pathway of Blood Coagulation: Implications in the Pathogenesis of hTTR Intracardiac Thrombosis

ISTH Academy, Faculty / Presenters, 406600

PB0590 The Control of Protein Binding on Bio-Interface by a Novel Coating to Prevent Contact Activation on Biomaterials

ISTH Academy, Faculty / Presenters, 406601

PB0587 Identifying Variants of AAT M358R with Increased Selectivity for Plasma Kallikrein

ISTH Academy, Faculty / Presenters, 406602

PB1048 Implementation of Electronic Medical Records in a Resource-Limited Haematology Department in North-West Nigeria

ISTH Academy, Faculty / Presenters, 406603

PB1047 A Patient with Severe, Refractory ITP and GI Bleeding is kept Hemodynamically Stable over Days with a Combination Therapy of Tranexamic Acid, Recombinant FVIIa, F XIII and Red Blood Cell Concentrates

ISTH Academy, Faculty / Presenters, 406604

PB1046 Early Goal-Directed Hemostatic Therapy (EGDHT) for Severe Acute Bleeding Management in the Intensive Care Unit

ISTH Academy, Faculty / Presenters, 406605

PB1043 Efficacy and Safety of Three-Factor Prothrombin Complex Concentrates for the Management of Oral Direct Factor Xa Inhibitor Associated Major Bleeding

ISTH Academy, Faculty / Presenters, 406606

PB1041 Evaluation of External Quality Assessment Material on the Renovated Point of Care Device, United Kingdom National External Quality Assessment Scheme for Blood Coagulation Studies

ISTH Academy, Faculty / Presenters, 406607

PB1042 Impact of Preoperative Anticoagulation on Perioperative Bleeding in Patients Undergoing Cardiopulmonary Bypass for Heart and Lung Transplantation

ISTH Academy, Faculty / Presenters, 406608

PB1039 Evaluation of External Quality Assessment Material for Activated Clotting Time on Point of Care Devices: United Kingdom National External Quality Assessment Scheme for Blood Coagulation Pilot Studies

ISTH Academy, Faculty / Presenters, 406609

PB1037 Bridging for Chronic AVKs Use with Enoxaparin vs Rivaroxaban: A Long-Term, Single-Center, Controller, Prospective Study

ISTH Academy, Faculty / Presenters, 406610

PB1038 Differences in Clot Formation and Lysis between Septic Patients and Controls Assessed by Whole-Blood Thromboelastometry: A Prospective Observational Study

ISTH Academy, Faculty / Presenters, 406611

PB1033 Delphi Consensus Recommendations for Neuraxial Anesthesia in Adults with Platelet Disorders and Coagulation Defects

ISTH Academy, Faculty / Presenters, 406612

PB1034 Monitoring of Argatroban in Critical Ill Patients: A Prospective Study Comparing aPTT, Point-of-Care Viscoelastic Testing with Ecarin Clotting Time and dTT to LC/MS/MS

ISTH Academy, Faculty / Presenters, 406613

PB1035 Monitoring of Unfractionated Heparin in Critical ill ICU Patients: A Prospective Study Comparing aPTT and Point-of-Care Viscoelastic Testing with IN/HI Ratio to Anti-Xa

ISTH Academy, Faculty / Presenters, 406614

PB1031 Assessment of Coagulation Factor Levels in LVAD Patients Following Temporary Warfarin Reversal with 4F-PCC: KVAD Study

ISTH Academy, Faculty / Presenters, 406615

PB1032 Four-Factor Prothrombin Complex Concentrates for Vitamin K Antagonist Reversal before Urgent Surgery: Dosing and Hemostatic Efficacy in a Double-Blind Randomized Study

ISTH Academy, Faculty / Presenters, 406616

PB1030 Hemostatic Evaluation of Synthetic Platelet Nanotechnology in Rabbit Models of Dilutional Coagulopathy and Trauma

ISTH Academy, Faculty / Presenters, 406617

PB1051 Tyrosine Under-Sulfation of Factor VIII Results in T-Cell Response and Decreased Affinity Towards Thrombin in a Model System

ISTH Academy, Faculty / Presenters, 406618

PB1049 Immune Modulatory Function of Desialylated Platelets Containing FVIII in FVIII Immune Responses in Hemophilia A Mice

ISTH Academy, Faculty / Presenters, 406619

PB1050 Putative Collagen IV and Heparin-Binding Sites Cooperatively Regulate Extravascular Binding of Factor IX in Hemophilia B Mice

ISTH Academy, Faculty / Presenters, 406620