PB0014 Do Antiphospholipid Antibodies Inform the Choice of Anticoagulant Agents in Patients with Atrial Fibrillation?

ISTH Academy, Faculty / Presenters, 406506

PB0011 Evaluation of the Association between Clinical Events and Apixaban/ Rivaroxaban’s Plasma exposure in Patients from the OptimAT Study

ISTH Academy, Faculty / Presenters, 406507

PB0012 Anticoagulant use and Prognosis of Non-Valvular Atrial Fibrillation Patients According to Baseline CHA2DS2-VASc Score and HAS-BLED Score

ISTH Academy, Faculty / Presenters, 406508

PB0010 Neutrophil-Activating Peptide 2 as a Novel Modulator of Fibrin Clot Properties in Patients with Atrial Fibrillation on Anticoagulation

ISTH Academy, Faculty / Presenters, 406509

PB0035 Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-Coated Aspirin in Patients with StablE Diabetes: Preliminary Findings from the APPEASED Study

ISTH Academy, Faculty / Presenters, 406510

PB0033 Validated in vivo Model to Assess Direct Oral Anticoagulant Reversal Agents

ISTH Academy, Faculty / Presenters, 406511

PB0034 Endogenous Dysregulation of Biomarkers of Thromboinflammatory Responses in End-Stage Renal Disease, and Their Amplification by Heart Failure

ISTH Academy, Faculty / Presenters, 406512

PB0030 The Association between Depressive Symptom Profiles and Hemostasis: The Biobehavioral Pathway to Cardiovascular Diseases?

ISTH Academy, Faculty / Presenters, 406513

PB0032 Interpaly of Oxidative Stress Markers with Thrombo-Inflammatory Barkers in End Stage Renal Disease

ISTH Academy, Faculty / Presenters, 406514

PB0031 Natural Antibodies to Oxidation-Specific Epitopes Characterize Hemodialysis Patients Protected from Cardiovascular Events

ISTH Academy, Faculty / Presenters, 406515

PB0029 Bridging Therapy and Risk of Major Bleeding and Thrombosis with Continuous-Flow Left Ventricular Assist Device: A Quasi-Experimental Study

ISTH Academy, Faculty / Presenters, 406516

PB0027 Assessing Genetic Risk Factors for Early-Onset Coronary Artery Disease in Iranians

ISTH Academy, Faculty / Presenters, 406517

PB0028 The Impact of Cannulation Site on Bleeding and Thrombotic Outcomes in Venovenous ECMO

ISTH Academy, Faculty / Presenters, 406518

PB0026 Low Platelet Count has a Strong Worsening Impact on Outcome in Patients with Acute Coronary Syndromes: From the START Antiplatelet Registry

ISTH Academy, Faculty / Presenters, 406519

PB0043 Hypercoagulable State and Mortality in ICU Patients during 2020–2022: A Single Centre Report

ISTH Academy, Faculty / Presenters, 406520

PB0039 Long Term Follow-Up of Cerebral Magnetic Resonance Imaging in Patients with Antiphospholipid Syndrome Assessing the Risk Factors for Recurrent Cerebral Events

ISTH Academy, Faculty / Presenters, 406521

PB0041 Prevalence of Vascular Risk Factors and I/D Angiotensin-Converting Enzyme Gene (ACE) Polymorphism in Costa Rican Elderly Patients with Cognitive Impariment

ISTH Academy, Faculty / Presenters, 406522

PB0040 Assessing Inter-Operator Variability in Gating Strategy of Whole Blood Monocyte Subsets Using Flow Cytometry in Patients with Acute Stroke Suspicion

ISTH Academy, Faculty / Presenters, 406523

PB0037 Thrombotic Cerebrovascular Outcomes in Patients with Fibromuscular Dysplasia Treated with Antiplatelet Agents or Anticoagulants: A Single-Center Experience

ISTH Academy, Faculty / Presenters, 406524

PB0036 Plasma Protein Carbonyl Levels Contribute to Prothrombotic Fibrin Clot Phenotype in Acute Ischemic Stroke Patients: Associations with Clinical Outcomes

ISTH Academy, Faculty / Presenters, 406525

PB0045 SEM and 3D Reconstruction of ex-vivo Arterial Thrombi: A Pilot Study

ISTH Academy, Faculty / Presenters, 406526

PB0044 Pediatric Arterial Thrombosis: Patient Characteristics and Thrombosis Outcomes

ISTH Academy, Faculty / Presenters, 406527

PB0529 Haemostatic Properties of Chromolaena Odorata: Evaluation of in vivo and in vitro Activity

ISTH Academy, Faculty / Presenters, 406528

PB0527 Assessment of the Rats Model of Hemophilic Arthritis by Micro CT Scanning

ISTH Academy, Faculty / Presenters, 406529

PB0525 Identification of an Aberrant Cell Population in a Knock-in Murine Model with RUNX1 Variant Generated by CRISPR/Cas9

ISTH Academy, Faculty / Presenters, 406530

PB0522 Characterization of Coagulopathy in a Swine Muscle Injury Model

ISTH Academy, Faculty / Presenters, 406531

PB0523 Effect of Flow on Structural and Mechanical Properties of the Fibrin Network in Plasma Thrombi

ISTH Academy, Faculty / Presenters, 406532

PB0524 Preparation and Characterization of Nanocarriers for Transdermal Delivery of Enoxaparin

ISTH Academy, Faculty / Presenters, 406533

PB0520 Atorvastatin Treatment Inhibits the Procoagulant Properties of a 3D Culture Model of the Human Neointimal Layer

ISTH Academy, Faculty / Presenters, 406534

PB0521 Development and Characterization of Novel Nanoparticulate Carrier for Oral Delivery of Low Molecular Weight Heparin

ISTH Academy, Faculty / Presenters, 406535

PB0519 Age-Dependent Changes in Mortality and Biomarkers of Immunothrombosis in a Murine Model of Sepsis

ISTH Academy, Faculty / Presenters, 406536

PB0517 Enhancement of Experimental Venous Thrombosis in Sickle Trait Mice is Prevented by Gardos Channel Inhibition

ISTH Academy, Faculty / Presenters, 406537

PB0518 Novel Insights into Antifibrinolytic and Prothrombotic Functions of Lipoprotein(a)

ISTH Academy, Faculty / Presenters, 406538

PB0516 Andexanet Alfa Versus 4-F Prothrombin Complex Concentrate in an Apixaban Anticoagulated Porcine Polytrauma Model

ISTH Academy, Faculty / Presenters, 406539

PB0586 Protein S Deficiency is Associated with an Increased Risk of Deep Vein Thrombosis in Pregnant Women Using Oral Contraceptive

ISTH Academy, Faculty / Presenters, 406540

PB0582 Differential Neutralization of Bovine Heparins as Measured by Functional Assays and Absolute Quantification of Glycosaminoglycan Context

ISTH Academy, Faculty / Presenters, 406541

PB0584 Using Heparin-Calibrated Assays to Assess Anti-Factor Xa Activity of Factor Xa Inhibitors (FXaI): A Literature Correlation Analysis

ISTH Academy, Faculty / Presenters, 406542

PB0578 Antithrombin Deficiency Responsible for Repeated Thromboembolic Complications – Case Report

ISTH Academy, Faculty / Presenters, 406543

PB0579 Approaches to Assure Similarity of Pharmaceutical Preparations of Unfractionated Heparin

ISTH Academy, Faculty / Presenters, 406544

PB0580 Laboratory Diagnosis of Prekallikrein Deficiency: Importance of Suspicion and Laboratory Method

ISTH Academy, Faculty / Presenters, 406545

PB0576 Correlation between High Affinity Material for Antithrombin and Anticoagulant Activities of Heparin

ISTH Academy, Faculty / Presenters, 406546

PB0577 Heparin Potency Assays – Reagents can Cause Differences in Potency Assignment

ISTH Academy, Faculty / Presenters, 406547

PB0575 Novel Variants of PROS1 Gene Related to Protein S Deficiency

ISTH Academy, Faculty / Presenters, 406548

PB0570 A Comparison of Heparins from Porcine and Bovine Origins in Various Laboratory Assays

ISTH Academy, Faculty / Presenters, 406549

PB0571 Analysis of the Risk Factors on the Development of Thromboembolic Complications

ISTH Academy, Faculty / Presenters, 406550

PB0572 Potency-Adjusted Bovine Heparin Exhibits Similar Anticoagulant Effects as Porcine Heparin in Whole Blood Clotting Studies

ISTH Academy, Faculty / Presenters, 406551

PB0573 Routine Haemostasis Profile in Sickle Cell Disease Patients in Steady State: A Retrospective, Descriptive Study

ISTH Academy, Faculty / Presenters, 406552

PB0574 Severe Bleeding in an Acquired Factor XIII Deficiency in an Otherwise Healthy Patient

ISTH Academy, Faculty / Presenters, 406553

PB0569 Elevated International Normalized Ratio in Hospitalized Patients Treated with Direct Oral Anticoagulants

ISTH Academy, Faculty / Presenters, 406554

PB0562 Effects of High-Fat and High-Carbohydrate Meals on Coagulation and Anticoagulation Factors and Lipid Profile

ISTH Academy, Faculty / Presenters, 406555

PB0563 Evaluation of the Rapid and Easy-to-Use Point-of-Care qLabs FIB® System to Quantify Functional Fibrinogen Levels in Patients Undergoing Plasma Exchange Therapy

ISTH Academy, Faculty / Presenters, 406556

PB0564 Evaluation of the Significance of Mixing Study in Lupus Anticoagulant Testing Using A New CMC Algorithm

ISTH Academy, Faculty / Presenters, 406557

PB0565 Long-Term ex-situ Normothermic Machine Perfusion of Human Livers Provides a Platform to Study (Patho)Physiology and Production of Hemostatic Proteins

ISTH Academy, Faculty / Presenters, 406558

PB0566 Prediction and Validation of the Effects of Targeting either Coagulation FXI Activation or Activity on Thrombin Generation

ISTH Academy, Faculty / Presenters, 406559

PB0568 X-Ray Structures of Thrombin Bound to Heterobifunctional Aptamer-Drug Conjugates Reveal the Mechanistic Basis for a Novel Tethered Inhibition Strategy

ISTH Academy, Faculty / Presenters, 406560

PB0554 A Phase 1/2 Study to Determine the Dose-Response Relationship by Assessment of Thrombin Generation After 4-Factor PCC in Healthy Subjects under Vitamin K Antagonist Anticoagulation

ISTH Academy, Faculty / Presenters, 406561

PB0555 Efficacy and Safety of 4-Factor Prothrombin Complex Concentrate for Management for Direct Xa Inhibitor-Induced Major Bleeding

ISTH Academy, Faculty / Presenters, 406562

PB0556 Evaluation of the ACL TOP 970 CL Analyser for Clotting, Chromogenic and Immunoturbidimetric Assays for Thrombophilia

ISTH Academy, Faculty / Presenters, 406563

PB0557 Fermentation of Sweet Corn Produced a Very High Concentration of Vitamin K

ISTH Academy, Faculty / Presenters, 406564

PB0558 Lack of Interaction of Milvexian, an Investigational Oral FXIa Inhibitor with Aspirin and Ticagrelor on Platelet Aggregation, Thrombin Generation and Thromboelastography in vitro

ISTH Academy, Faculty / Presenters, 406565

PB0559 Novel Variants of PROS1 Gene Related to Protein S Deficiency

ISTH Academy, Faculty / Presenters, 406566

PB0560 Step-by-Step Production and Biological Evaluation of Novel Aryl Piperazine-based FXa Inhibitors

ISTH Academy, Faculty / Presenters, 406567

PB0551 A Comparison of USP Potency Adjusted and Mass Adjusted Heparins of Bovine, Ovine, and Porcine Origin in Various Assays

ISTH Academy, Faculty / Presenters, 406568

PB0552 Performance Evaluation of the ACTICHROME Heparin Anti-Xa Assay for the Quantitative Determination of Unfractionated Heparin and Low-Molecular-Weight Heparin Plasma Concentrations

ISTH Academy, Faculty / Presenters, 406569

PB0553 Role of International Society of Thrombosis and Hemostasis-Bleeding Assessment Tool, RICOF, ROTEM, and APTT-Clot wave form Analysis (CWA) in Evaluation of Patients with Bleeding of Unknown Cause (BUC)

ISTH Academy, Faculty / Presenters, 406570

PB0548 Efficacy of Direct Oral Anticoagulants in Liver Cirrhosis: An in-vitro Study

ISTH Academy, Faculty / Presenters, 406571

PB0549 Healthcare Resource Use Among US Veterans Treated with Andexanet Alfa or 4-Factor Prothrombin Complex Concentrate for Factor Xa Inhibitor-Related Major Bleeding

ISTH Academy, Faculty / Presenters, 406572

PB0550 Novel Variants of PROS1 Gene Related to Protein S Deficiency

ISTH Academy, Faculty / Presenters, 406573

PB0546 Effect of Atorvastatin on IL-6 and F1+2 in High Risk Thrombosis Patients with Cancer Undergoing Chemotherapy

ISTH Academy, Faculty / Presenters, 406574

PB0547 Poly(Sodium Styrenesulfonate)-based Copolymers with Anticoagulant Activity: Preliminary Efficacy and Safety Studies

ISTH Academy, Faculty / Presenters, 406575

PB0538 A Monoclonal Antibody against Human Factor V Impairs its Activation and Procoagulant Function

ISTH Academy, Faculty / Presenters, 406576

PB0539 Detection of TFPI Citrullination in Blood after Neutrophil Activation by PMA

ISTH Academy, Faculty / Presenters, 406577

PB0541 Expression of Recombinant Human Factor VII Activating Protease (FSAP) and Exploration of its 3D Structure Using AlphaFold

ISTH Academy, Faculty / Presenters, 406578

PB0542 Investigating Thrombin-Loaded Fibrin in Whole Blood Clot Microfluidic Assay via Fluorogenic Peptide

ISTH Academy, Faculty / Presenters, 406579

PB0543 Like Heparin, Polyphosphate Promotes the Formation of a Ternary Complex with Thrombin and Fibrin

ISTH Academy, Faculty / Presenters, 406580

PB0544 Management of Inherited Antithrombin Deficiency in Pregnancy and Puerperium: Single Center Experience

ISTH Academy, Faculty / Presenters, 406581

PB0545 The Effect of a History of Preeclampsia on Hemostatic Balance in the Non-Pregnant State

ISTH Academy, Faculty / Presenters, 406582

PB0535 Development of Function-Blocking Antibodies to Plasma Prekallikrein for the Study of the Interplay between Coagulation and Inflammation

ISTH Academy, Faculty / Presenters, 406583

PB0536 Oral Factor XIIa Inhibitor KV998086 Protects Against FeCl3 Induced Thrombosis in Mice

ISTH Academy, Faculty / Presenters, 406584

PB0537 Tissue Factor Pathway Inhibitor and Tissue Factor Pathway Inhibitorrs7586970 Variant in Myocardial Infarction with Type 2 Diabetes Mellitus

ISTH Academy, Faculty / Presenters, 406585

PB0533 New Low Molecular Weight Heparin Antidote Based on an Antithrombin Mutant

ISTH Academy, Faculty / Presenters, 406586

PB0534 Rapid Measurement of DOAC Concentration and Platelet Function Using Whole Blood in a Disposable Microfluidic Device

ISTH Academy, Faculty / Presenters, 406587

PB0531 Mechanical Behavior of Clots: Molecular Mechanism of Forced Unfolding of Crosslinked Fibrin Protofibrils

ISTH Academy, Faculty / Presenters, 406588

PB0532 The Factor XIa Antibody Osocimab Combined with Enoxaparin Strongly Inhibits Clotting in Extracorporeal Circuits in vitro

ISTH Academy, Faculty / Presenters, 406589

PB0530 Sex-Specific Differences in Procoagulant Profiles

ISTH Academy, Faculty / Presenters, 406590

PB0598 Blood Anticoagulant Impacts Endogenous Thrombin Generation in a Peripartum Population

ISTH Academy, Faculty / Presenters, 406591

PB0596 Characterization of Anti-Polyphosphate Monoclonal Antibodies

ISTH Academy, Faculty / Presenters, 406592

PB0597 Specificity of Contact Pathway Inhibitors with Regard to Other Coagulation and Fibrinolysis Proteases

ISTH Academy, Faculty / Presenters, 406593

PB0593 Extending the Circulatory Half-Life of an Engineered Kallikrein-Specific Inhibitor

ISTH Academy, Faculty / Presenters, 406594

PB0594 Factor XI Localization in Human Deep Venous Thrombus and Function of Activated Factor XI on Mural Thrombus Formation Under Low-Shear Condition

ISTH Academy, Faculty / Presenters, 406595

PB0591 Alphafold AI based Applications Explored as Tools for Predicting Contact Proteins PK, FXI and HK Structure and Evolutionary Relationships

ISTH Academy, Faculty / Presenters, 406596

PB0595 The Profile of Contact Activation System Proteins in Human Abdominal Aortic Aneurysm Plasma-and Tissue Samples

ISTH Academy, Faculty / Presenters, 406597

PB0592 Evaluation of the Role of Skeletal Muscle Myosin as a Cofactor for Factor XI Activation of Factor XII

ISTH Academy, Faculty / Presenters, 406598

PB0588 Epitope Mapping of the α-FXIIa Allosteric Inhibitor Monoclonal Antibody 5C12

ISTH Academy, Faculty / Presenters, 406599

PB0589 Human Transthyretin (hTTR) Amyloid Fibrils Induce Plasma Clotting by Activating the Intrinsic Pathway of Blood Coagulation: Implications in the Pathogenesis of hTTR Intracardiac Thrombosis

ISTH Academy, Faculty / Presenters, 406600

PB0590 The Control of Protein Binding on Bio-Interface by a Novel Coating to Prevent Contact Activation on Biomaterials

ISTH Academy, Faculty / Presenters, 406601

PB0587 Identifying Variants of AAT M358R with Increased Selectivity for Plasma Kallikrein

ISTH Academy, Faculty / Presenters, 406602

PB1048 Implementation of Electronic Medical Records in a Resource-Limited Haematology Department in North-West Nigeria

ISTH Academy, Faculty / Presenters, 406603

PB1047 A Patient with Severe, Refractory ITP and GI Bleeding is kept Hemodynamically Stable over Days with a Combination Therapy of Tranexamic Acid, Recombinant FVIIa, F XIII and Red Blood Cell Concentrates

ISTH Academy, Faculty / Presenters, 406604

PB1046 Early Goal-Directed Hemostatic Therapy (EGDHT) for Severe Acute Bleeding Management in the Intensive Care Unit

ISTH Academy, Faculty / Presenters, 406605