PB1043 Efficacy and Safety of Three-Factor Prothrombin Complex Concentrates for the Management of Oral Direct Factor Xa Inhibitor Associated Major Bleeding

ISTH Academy, Faculty / Presenters, 406606

PB1041 Evaluation of External Quality Assessment Material on the Renovated Point of Care Device, United Kingdom National External Quality Assessment Scheme for Blood Coagulation Studies

ISTH Academy, Faculty / Presenters, 406607

PB1042 Impact of Preoperative Anticoagulation on Perioperative Bleeding in Patients Undergoing Cardiopulmonary Bypass for Heart and Lung Transplantation

ISTH Academy, Faculty / Presenters, 406608

PB1039 Evaluation of External Quality Assessment Material for Activated Clotting Time on Point of Care Devices: United Kingdom National External Quality Assessment Scheme for Blood Coagulation Pilot Studies

ISTH Academy, Faculty / Presenters, 406609

PB1037 Bridging for Chronic AVKs Use with Enoxaparin vs Rivaroxaban: A Long-Term, Single-Center, Controller, Prospective Study

ISTH Academy, Faculty / Presenters, 406610

PB1038 Differences in Clot Formation and Lysis between Septic Patients and Controls Assessed by Whole-Blood Thromboelastometry: A Prospective Observational Study

ISTH Academy, Faculty / Presenters, 406611

PB1033 Delphi Consensus Recommendations for Neuraxial Anesthesia in Adults with Platelet Disorders and Coagulation Defects

ISTH Academy, Faculty / Presenters, 406612

PB1034 Monitoring of Argatroban in Critical Ill Patients: A Prospective Study Comparing aPTT, Point-of-Care Viscoelastic Testing with Ecarin Clotting Time and dTT to LC/MS/MS

ISTH Academy, Faculty / Presenters, 406613

PB1035 Monitoring of Unfractionated Heparin in Critical ill ICU Patients: A Prospective Study Comparing aPTT and Point-of-Care Viscoelastic Testing with IN/HI Ratio to Anti-Xa

ISTH Academy, Faculty / Presenters, 406614

PB1031 Assessment of Coagulation Factor Levels in LVAD Patients Following Temporary Warfarin Reversal with 4F-PCC: KVAD Study

ISTH Academy, Faculty / Presenters, 406615

PB1032 Four-Factor Prothrombin Complex Concentrates for Vitamin K Antagonist Reversal before Urgent Surgery: Dosing and Hemostatic Efficacy in a Double-Blind Randomized Study

ISTH Academy, Faculty / Presenters, 406616

PB1030 Hemostatic Evaluation of Synthetic Platelet Nanotechnology in Rabbit Models of Dilutional Coagulopathy and Trauma

ISTH Academy, Faculty / Presenters, 406617

PB1051 Tyrosine Under-Sulfation of Factor VIII Results in T-Cell Response and Decreased Affinity Towards Thrombin in a Model System

ISTH Academy, Faculty / Presenters, 406618

PB1049 Immune Modulatory Function of Desialylated Platelets Containing FVIII in FVIII Immune Responses in Hemophilia A Mice

ISTH Academy, Faculty / Presenters, 406619

PB1050 Putative Collagen IV and Heparin-Binding Sites Cooperatively Regulate Extravascular Binding of Factor IX in Hemophilia B Mice

ISTH Academy, Faculty / Presenters, 406620

PB1062 Exogenous Warfarin Intoxication Associated with Munchaüsen Syndrome

ISTH Academy, Faculty / Presenters, 406621

PB1063 In vitro Fibrinogen Concentrate Supplementation in Patients with End-Stage Liver Disease Improves Functional Clot Quality

ISTH Academy, Faculty / Presenters, 406622

PB1058 Mechanical Properties of Fibrin Clots from Patients with Acute-on-Chronic Liver Failure are Inferior to those of Healthy Individuals and Patients with Sepsis without Underlying Liver Disease

ISTH Academy, Faculty / Presenters, 406623

PB1061 Impact of FII, FVIII, or FIX Deficiency on Bone Mineralization in aZebrafish Model

ISTH Academy, Faculty / Presenters, 406624

PB1059 Single Amino Acid Substitutions of an Antibody Specific for a Non-Active Site of Activated Protein C (APC) Yielded an Antibody Library Capable of Modulating and Uncoupling APC Pleiotropic Functions

ISTH Academy, Faculty / Presenters, 406625

PB1060 Thrombin Generation and Fibrin Clot Structure in Nephrotic Patients with Primary Glomerular Disorders

ISTH Academy, Faculty / Presenters, 406626

PB1056 In situ Pulmonary Thrombosis is Regulated by Integrin αIIbβ3-Dependent Platelet Procoagulant Activity

ISTH Academy, Faculty / Presenters, 406627

PB1057 VWF Type 2N Variant Markedly Enhances FVIII Levels When Both Proteins are Expressed in Platelets

ISTH Academy, Faculty / Presenters, 406628

PB1054 A Multi-Center, Stratification-Randomized, Double-Blind, Placebo-Controlled, Phase III Clinical Trial of Topical Recombinant Human Thrombin for Intraoperative Hemostasis

ISTH Academy, Faculty / Presenters, 406629

PB1055 Chronic Anticoagulation in Patients with Liver Failure: A Single-Center Cohort Study

ISTH Academy, Faculty / Presenters, 406630

PB1052 Evaluating the Individual Risk of Venous Thrombo-Embolism in Patients with Liver Cirrhosis: Usefulness of in vivo and ex vivo Thrombin Generation Parameters

ISTH Academy, Faculty / Presenters, 406631

PB1053 Protective Role of the SerpinE2 PN-1 in Renal Disease

ISTH Academy, Faculty / Presenters, 406632

PB1070 Small and Large Extracellular Vesicles have Different Tissue Factor Activity in Cancer, Sepsis, and COVID-19

ISTH Academy, Faculty / Presenters, 406633

PB1067 Quantification of Functional Tissue Factor Activity on Microvesicles during the Peripartum Period

ISTH Academy, Faculty / Presenters, 406634

PB1069 A Standardized Approach in Enumerating Microparticles in the Framingham Heart Study Using Quantitative Flow Cytometry

ISTH Academy, Faculty / Presenters, 406635

PB1065 Microvesicles Display Opposite Coagulolytic Balances According to Their Cellular Origin and Activation Status

ISTH Academy, Faculty / Presenters, 406636

PB1066 The Effects of Polystyrene Microplastics on Thrombosis

ISTH Academy, Faculty / Presenters, 406637

PB1078 Severe Thromboembolic Events in A Patient with Protein C and Protein S Heterozygous Deficiencies

ISTH Academy, Faculty / Presenters, 406638

PB1079 Evaluation of the Automated LiaphenTM Protein C Antigen (PCAg) Assay Kit on the Sysmex CN-6500 Analyser

ISTH Academy, Faculty / Presenters, 406639

PB1077 A Novel C238G, PROC Mutation in Patients with Thromboembolism, Causes Intracellular Protein Retention

ISTH Academy, Faculty / Presenters, 406640

PB1075 APC Response Rates in Factor V Leiden Carriers Correlate with Thrombotic Risk Independent from Endothelial Properties: Results from an Endothelial Cell-Based ex vivo Model of the Protein C Pathway

ISTH Academy, Faculty / Presenters, 406641

PB1076 Congenital Protein C Deficiency is Associated with Prothrombotic Plasma Fibrin Clot Phenotype

ISTH Academy, Faculty / Presenters, 406642

PB1073 Endothelial Cell-Dependent Activated Protein C Formation is Significantly Decreased in Hereditary Protein C Deficiency Regardless of Underlying Gene Variant and Residual Activity in Plasma

ISTH Academy, Faculty / Presenters, 406643

PB1072 A Novel Factor VIII Specific APC Resistance Assay

ISTH Academy, Faculty / Presenters, 406644

PB1074 Population Pharmacokinetics of Subcutaneous Protein C Concentrate in Patients with Protein C Deficiency

ISTH Academy, Faculty / Presenters, 406645

PB1071 A Single-Domain Antibody Enhancing Protein S Activity Reduces Vaso-Occlusion in a Murine Model of Sickle Cell Disease

ISTH Academy, Faculty / Presenters, 406646

PB1100 Effects of COVID-19 Vaccination on Pro-Coagulant State of a Protein S-Deficient Pediatric Patient: New Hope for Treatment of the Deficiency

ISTH Academy, Faculty / Presenters, 406647

PB1097 Cost of Major Thrombotic Cardiovascular Events (MTCVE) Among US Patients with and without End-Stage Kidney Disease (ESKD)

ISTH Academy, Faculty / Presenters, 406648

PB1098 Regulation of Protein S Gene Expression by Hypoxia Inducible Factor 1 α and Estrogen Receptor

ISTH Academy, Faculty / Presenters, 406649

PB1095 Direct Measurement of Citrated Blood Recalcification in Microfluidic Flow Chamber

ISTH Academy, Faculty / Presenters, 406650

PB1091 A Novel Function of Protein S in Clot Retraction

ISTH Academy, Faculty / Presenters, 406651

PB1092 Identification of Amplifying Pathways of Thrombin Generation in a Novel Mouse Whole Blood Assay

ISTH Academy, Faculty / Presenters, 406652

PB1093 Impact of the Procoagulant Fingerprint of Cancer Cells on the Structure of Fibrin Clot Formed in Tumor Microenvironment

ISTH Academy, Faculty / Presenters, 406653

PB1094 Multi-Technique Study of the Role of Fibrinogen and Thrombin in Clot Formation and Structure

ISTH Academy, Faculty / Presenters, 406654

PB1090 Modelling the Effects of 4-Factor Prothrombin Complex Concentrate for the Management of Factor Xa Inhibitor-Associated Bleeding

ISTH Academy, Faculty / Presenters, 406655

PB1089 Impact of Scorpion Venoms on the Control of Thrombotic Disease

ISTH Academy, Faculty / Presenters, 406656

PB1087 An Enoxaparin Obtained from Bovine Heparin is Equivalent to the Original Drug From Porcine Origin

ISTH Academy, Faculty / Presenters, 406657

PB1088 The Effect of DOAC-Stop on Lupus Anticoagulant Testing in Plasma Patients Receiving Direct Oral Anticoagulant

ISTH Academy, Faculty / Presenters, 406658

PB1082 Comprehensive Coagulation Activity Assessments of Escalating Doses of Intravenous APAC, a Heparin Proteoglycan Mimic, in Pigs

ISTH Academy, Faculty / Presenters, 406659

PB1083 Effect of Combining Antiplatelet Therapy with Anticoagulation without A Definitive Indication in Patients with Chronic Liver Disease

ISTH Academy, Faculty / Presenters, 406660

PB1086 Time in Therapeutic Range after an Event: Where We Started from and Where Are We Going?

ISTH Academy, Faculty / Presenters, 406661

PB1080 Clinical Course and Management of Patients with Emergency Surgeries Treated with Direct Oral Anticoagulants or Vitamin K Antagonists – Results of the German Prospective RADOA-Registry

ISTH Academy, Faculty / Presenters, 406662

PB1081 Identification of Related Molecular Biological Effects on Two Novel Point Mutations in Inherited Antithrombin Deficiency

ISTH Academy, Faculty / Presenters, 406663

PB1102 Evaluation of the Ability of Commercial ELISAs to Measure Tissue Factor in Human Plasma

ISTH Academy, Faculty / Presenters, 406664

PB1101 Assessing the Antithrombotic Effects of Isoquercetin in Sickle Cell Disease

ISTH Academy, Faculty / Presenters, 406665

PB0613 IL-6 Dosage by ELISA Tests in Patients after COVID-19 Infection: Significant Correlation between Length of Hospitalization and Permanently Altered Levels of Interleukin-6

ISTH Academy, Faculty / Presenters, 406666

PB0612 COVID-19: Predictive Value of Methemoglobinemia

ISTH Academy, Faculty / Presenters, 406667

PB0609 Plasma Fractionation by HaemaFrac® Technology -A Bioprocessing Innovation

ISTH Academy, Faculty / Presenters, 406668

PB0607 Evaluation of Proinflammatory and Haemostasis Markers after BNT162b2 SARS-CoV-2 Vaccination

ISTH Academy, Faculty / Presenters, 406669

PB0602 Plasma NET Markers Kinetics in COVID-19 Patients Receiving Immunomodulatory Treatments

ISTH Academy, Faculty / Presenters, 406670

PB0604 The VWF-ADAMTS13 Axis as Biomarkers of Disease Progression in Severe COVID-19

ISTH Academy, Faculty / Presenters, 406671

PB0601 Identification of a Novel Growth Factor-Enriched Platelet Subpopulation: Potential Implications for COVID-19

ISTH Academy, Faculty / Presenters, 406672

PB0600 Circulating Platelet-Derived Extracellular Vesicles are Increased in Severe COVID-19 Disease

ISTH Academy, Faculty / Presenters, 406673

PB0599 Dysregulation of Annexin A2 System Triggered by Acute SARS-CoV-2 Infection in Human ACE2 Transgenic Mice

ISTH Academy, Faculty / Presenters, 406674

PB0117 COVID-Associated Thrombosis: New Insights

ISTH Academy, Faculty / Presenters, 406675

PB0114 Human Immunodeficiency Virus (HIV) and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2): Dangerous Liaisons?

ISTH Academy, Faculty / Presenters, 406676

PB0115 Paxlovid Attenuates the Inflammatory and Thrombotic Response in High-Risk Patients with COVID-19

ISTH Academy, Faculty / Presenters, 406677

PB0100 Anticoagulation in Hospitalized COVID-19 Obese Patients and Venous Thromboembolism (VTE) in Salvador – Brazil

ISTH Academy, Faculty / Presenters, 406678

PB0101 Comparison of Padua Prediction Score and IMPROVE VTE Risk Score for Venous Thromboembolism at Admission to Assess Hypercoagulation in COVID-19 Patients

ISTH Academy, Faculty / Presenters, 406679

PB0103 Disturbance of the Hemostatic Balance in Outpatients with Covid-19

ISTH Academy, Faculty / Presenters, 406680

PB0104 Emergency Mobile and Point of Care Anticoagulation Clinic During (COVID-19) Curfew by Pharmacists in Saudi Arabia

ISTH Academy, Faculty / Presenters, 406681

PB0107 The Relationship between Length of Hospital Stay and Anticoagulant Use in Patients with Moderate COVID-19

ISTH Academy, Faculty / Presenters, 406682

PB0093 Antiphospholipid Antibodies in Convalescent Plasma of Donors Recovered from Mild COVID-19

ISTH Academy, Faculty / Presenters, 406683

PB0094 Antiphospholipid Antibodies in Severe and Critically ill COVID-19 Patients

ISTH Academy, Faculty / Presenters, 406684

PB0096 Cytokines Profile of Severe COVID-19 does not Differ from ICU-Control

ISTH Academy, Faculty / Presenters, 406685

PB0097 Intracellular Nuclear Proteins Histone H3 and HMGB1 are Predictive Markers of Disease Severity and Prognosis of COVID-19 Patients

ISTH Academy, Faculty / Presenters, 406686

PB0099 Thrombin Generation Parameters Results in COVID Patients Comparing with Healthy Volunteers

ISTH Academy, Faculty / Presenters, 406687

PB0088 Alterations in Thrombin Generation after SARS-CoV-2 Vaccination and the Relation with Inflammation

ISTH Academy, Faculty / Presenters, 406688

PB0089 Anticoagulants after COVID-19 Pneumonia for Patients with Low Thrombotic Risk

ISTH Academy, Faculty / Presenters, 406689

PB0090 D-Dimer as an Indirect Marker of Microthrombi in Patients with Long COVID

ISTH Academy, Faculty / Presenters, 406690

PB0083 Efficacy and Safety of Thromboprophylaxis in Covid-19 Patients

ISTH Academy, Faculty / Presenters, 406691

PB0091 Fibrin Monomers Positivity During Hospitalization is a Good Predictive Marker of In-Hospital Mortality during COVID-19

ISTH Academy, Faculty / Presenters, 406692

PB0084 Incidences of Adverse Effects of Vaccination against SARS-CoV-2 in Patients with Congenital Coagulopathies

ISTH Academy, Faculty / Presenters, 406693

PB0085 Pitfalls of Complications due to Coagulopathy in Patients with Severe COVID-19 during ECMO: Beware of Bleeding Caused by Acquired von Willebrand Syndrome

ISTH Academy, Faculty / Presenters, 406694

PB0086 Prospective Assessment of Thrombomodulin Resistance in Oncological Patients and Healthy Subjects Following Vaccination Against Sars-Cov-2 with the mRNAVaccine. The Roadmap-COVID-19-Vaccin Study

ISTH Academy, Faculty / Presenters, 406695

PB0087 Use of Viscoelastic Tests in the Intensive Care Unit for the Evaluation of Haemostasis in SARS-COV-2 Infection

ISTH Academy, Faculty / Presenters, 406696

PB0073 A Retrospective Study of Two Anticoagulation Therapies In Critically Ill Covid-19 Patients Prior to Vaccination Era

ISTH Academy, Faculty / Presenters, 406697

PB0074 Hyper-Immunoglobulin-CovImmuneTM, Provides a Broader Coverage Against Diverse SARS-CoV-2 Variants Relevant to the COVID-19 Pandemic

ISTH Academy, Faculty / Presenters, 406698

PB0075 Nebulized Heparin in Covid 19 Pneumonia: Efficacy and Safety Versus Heparinoprophylaxis Alone (HEPANEBU)

ISTH Academy, Faculty / Presenters, 406699

PB0076 Platelet Activation and Cytokine Release of Interleukin-8 and IP-10 after ChAdOx1 nCoV-19 Coronavirus Vaccine Injection

ISTH Academy, Faculty / Presenters, 406700

PB0077 Predictors of Mortality in Hospitalized Patients with COVID-19

ISTH Academy, Faculty / Presenters, 406701

PB0079 Severity of Pulmonary Embolism among Hospitalized COVID-19 Patients in Salvador-Brazil

ISTH Academy, Faculty / Presenters, 406702

PB0080 The Effect of COVID-19 Pandemic in Haemophilia Patients in Argentina

ISTH Academy, Faculty / Presenters, 406703

PB0081 von Willebrand Factor and Myeloperoxidase as Laboratory Predictive Markers of In-Hospital Survival in Severe COVID-19 Patients

ISTH Academy, Faculty / Presenters, 406704

PB0082 VTE Incidence and Risk Factors among Hospitalized COVID-19 Patients in Salvador -Brazil

ISTH Academy, Faculty / Presenters, 406705