Acute Pulmonary Embolism in COVID-19 Patients on CT Angiography and Relationship to D-Dimer Levels
ISTH Academy. 05/21/20; 9444
Label: External COVID-19 Resources
Description
Summary
Thirty-two of 106 (30%, [95%CI 22-40%]) patients with COVID-19 infection were positive for acute pulmonary embolus on pulmonary CT angiograms.
INTRODUCTION
Reports of acute pulmonary embolism associated with COVID-19 have emerged in the literature. For example, Chen et al. described 25 pulmonary CT angiograms examinations from 1008 COVID-19 patients; 10 were positive for pulmonary embolism mostly as segmental or sub-segmental APE [1]. In addition, D-dimer levels have been reported as elevated in patients with COVID-19 [2; 3] with the suggestion of an independent association between the severity of the disease and the level of D-dimer [4]. The purpose of this report is to describe the rate of pulmonary embolus in patients classified as COVID-19 infection and who underwent chest CT at a tertiary referral centre.
Disclaimer
Answers to questions about COVID-19 published herein are provided by the International Society on Thrombosis and Haemostasis, Inc. (“ISTH”) for voluntary, informational use by providers in the rapidly evolving novel coronavirus crisis. This information does not constitute medical or legal advice, is not intended for use in the diagnosis or treatment of individual conditions, does not endorse products or therapies, recommend or mandate any particular course of medical care, and is not a statement of the standard of care. New evidence may emerge between the time information is developed and when it is published or read. The information is not comprehensive or continually updated. This information is not intended to substitute for the independent professional judgment of the treating provider in the context of treating the individual patient. ISTH provides this information on an “as is” basis, and makes no warranty, express or implied, regarding the information, including but not limited to its completeness or accuracy. ISTH specifically disclaims any warranties of merchantability or fitness for a particular use or purpose. ISTH assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of this information or for any errors or omissions. Use of the information is subject to the complete ISTH website Terms of Use.
The appearance of external hyperlinks does not constitute endorsement by ISTH of the linked websites, or the information, products or services contained therein. ISTH does not exercise any editorial control over the information you may find at these locations nor does ISTH make any representation of their accuracy or completeness. Please contact those websites with any questions
Thirty-two of 106 (30%, [95%CI 22-40%]) patients with COVID-19 infection were positive for acute pulmonary embolus on pulmonary CT angiograms.
INTRODUCTION
Reports of acute pulmonary embolism associated with COVID-19 have emerged in the literature. For example, Chen et al. described 25 pulmonary CT angiograms examinations from 1008 COVID-19 patients; 10 were positive for pulmonary embolism mostly as segmental or sub-segmental APE [1]. In addition, D-dimer levels have been reported as elevated in patients with COVID-19 [2; 3] with the suggestion of an independent association between the severity of the disease and the level of D-dimer [4]. The purpose of this report is to describe the rate of pulmonary embolus in patients classified as COVID-19 infection and who underwent chest CT at a tertiary referral centre.
Disclaimer
Answers to questions about COVID-19 published herein are provided by the International Society on Thrombosis and Haemostasis, Inc. (“ISTH”) for voluntary, informational use by providers in the rapidly evolving novel coronavirus crisis. This information does not constitute medical or legal advice, is not intended for use in the diagnosis or treatment of individual conditions, does not endorse products or therapies, recommend or mandate any particular course of medical care, and is not a statement of the standard of care. New evidence may emerge between the time information is developed and when it is published or read. The information is not comprehensive or continually updated. This information is not intended to substitute for the independent professional judgment of the treating provider in the context of treating the individual patient. ISTH provides this information on an “as is” basis, and makes no warranty, express or implied, regarding the information, including but not limited to its completeness or accuracy. ISTH specifically disclaims any warranties of merchantability or fitness for a particular use or purpose. ISTH assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of this information or for any errors or omissions. Use of the information is subject to the complete ISTH website Terms of Use.
The appearance of external hyperlinks does not constitute endorsement by ISTH of the linked websites, or the information, products or services contained therein. ISTH does not exercise any editorial control over the information you may find at these locations nor does ISTH make any representation of their accuracy or completeness. Please contact those websites with any questions
Summary
Thirty-two of 106 (30%, [95%CI 22-40%]) patients with COVID-19 infection were positive for acute pulmonary embolus on pulmonary CT angiograms.
INTRODUCTION
Reports of acute pulmonary embolism associated with COVID-19 have emerged in the literature. For example, Chen et al. described 25 pulmonary CT angiograms examinations from 1008 COVID-19 patients; 10 were positive for pulmonary embolism mostly as segmental or sub-segmental APE [1]. In addition, D-dimer levels have been reported as elevated in patients with COVID-19 [2; 3] with the suggestion of an independent association between the severity of the disease and the level of D-dimer [4]. The purpose of this report is to describe the rate of pulmonary embolus in patients classified as COVID-19 infection and who underwent chest CT at a tertiary referral centre.
Disclaimer
Answers to questions about COVID-19 published herein are provided by the International Society on Thrombosis and Haemostasis, Inc. (“ISTH”) for voluntary, informational use by providers in the rapidly evolving novel coronavirus crisis. This information does not constitute medical or legal advice, is not intended for use in the diagnosis or treatment of individual conditions, does not endorse products or therapies, recommend or mandate any particular course of medical care, and is not a statement of the standard of care. New evidence may emerge between the time information is developed and when it is published or read. The information is not comprehensive or continually updated. This information is not intended to substitute for the independent professional judgment of the treating provider in the context of treating the individual patient. ISTH provides this information on an “as is” basis, and makes no warranty, express or implied, regarding the information, including but not limited to its completeness or accuracy. ISTH specifically disclaims any warranties of merchantability or fitness for a particular use or purpose. ISTH assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of this information or for any errors or omissions. Use of the information is subject to the complete ISTH website Terms of Use.
The appearance of external hyperlinks does not constitute endorsement by ISTH of the linked websites, or the information, products or services contained therein. ISTH does not exercise any editorial control over the information you may find at these locations nor does ISTH make any representation of their accuracy or completeness. Please contact those websites with any questions
Thirty-two of 106 (30%, [95%CI 22-40%]) patients with COVID-19 infection were positive for acute pulmonary embolus on pulmonary CT angiograms.
INTRODUCTION
Reports of acute pulmonary embolism associated with COVID-19 have emerged in the literature. For example, Chen et al. described 25 pulmonary CT angiograms examinations from 1008 COVID-19 patients; 10 were positive for pulmonary embolism mostly as segmental or sub-segmental APE [1]. In addition, D-dimer levels have been reported as elevated in patients with COVID-19 [2; 3] with the suggestion of an independent association between the severity of the disease and the level of D-dimer [4]. The purpose of this report is to describe the rate of pulmonary embolus in patients classified as COVID-19 infection and who underwent chest CT at a tertiary referral centre.
Disclaimer
Answers to questions about COVID-19 published herein are provided by the International Society on Thrombosis and Haemostasis, Inc. (“ISTH”) for voluntary, informational use by providers in the rapidly evolving novel coronavirus crisis. This information does not constitute medical or legal advice, is not intended for use in the diagnosis or treatment of individual conditions, does not endorse products or therapies, recommend or mandate any particular course of medical care, and is not a statement of the standard of care. New evidence may emerge between the time information is developed and when it is published or read. The information is not comprehensive or continually updated. This information is not intended to substitute for the independent professional judgment of the treating provider in the context of treating the individual patient. ISTH provides this information on an “as is” basis, and makes no warranty, express or implied, regarding the information, including but not limited to its completeness or accuracy. ISTH specifically disclaims any warranties of merchantability or fitness for a particular use or purpose. ISTH assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of this information or for any errors or omissions. Use of the information is subject to the complete ISTH website Terms of Use.
The appearance of external hyperlinks does not constitute endorsement by ISTH of the linked websites, or the information, products or services contained therein. ISTH does not exercise any editorial control over the information you may find at these locations nor does ISTH make any representation of their accuracy or completeness. Please contact those websites with any questions
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