9 Steps

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Program Overview

This section of the ISTH Clinical Core Curriculum deals with aspects of the von Willebrand disease (VWD) to attain a level of proficiency to enable them to practice independently as specialists in the field.

Self needs-assessment questions
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Relate the understanding of the incidence, inheritance, classification (including molecular and genetic aspects), clinical manifestations, natural history and clinical complications to patients with VWD
Relate the understanding of the structural and functional aspects of the biology of von Willebrand factor (including cellular processing and interactions with platelets, endothelium and FVIII) to diagnosis and management of patients with VWD
Diagnose and classify VWD by interpretation of laboratory tests
Perform laboratory tests for diagnosis and classification of VWD
Develop clinical management plans for patients with VWD
Manage treatment of bleeds in patients with VWD, including use of desmopressin acetate, FVIII/VWF concentrates, cryoprecipitate, antifibrinolytics and fibrin glue
Diagnose and treat patients with VWD and inhibitors
Final self-assessment & evaluation
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