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17 Steps
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Program Overview
Progr...
This section of the ISTH Clinical Core Curriculum deals with aspects of haemophilia A and B to attain a level of proficiency to enable them to practice independently as specialists in the field.
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Self needs-assessment questions
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Apply their understanding of the epidemiology and molecular basis of haemophilia to clinical management of patients with this disorder
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Relate the impact of the history of haemophilia and the evolution of replacement therapy to issues relating to clinical management of patients affected by haemophilia
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Relate the principles of the structural and functional aspects of the biology of factor VIII (FVIII) and factor IX (FIX) to clinical management of patients with haemophilia A or B
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Recognize clinical manifestations of haemophilia
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Diagnose haemophilia A and B by interpreting laboratory tests
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Perform laboratory tests for diagnosis of haemophilia A and B
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Provide haemophilia treatment such as delivery of replacement therapy (primary and secondary prophylaxis, on-demand therapy of bleeds)
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Relate the principles of the epidemiology, immunology and molecular basis of inhibitors to FVIII, or FIX to clinical management of patients with haemophilia A or B
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Diagnose patients with inhibitors to FVIII and FIX by interpreting laboratory tests
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Manage patients with inhibitors to FVIII and FIX
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Manage dosing regimens for immune tolerance induction in patients with inhibitors, as well as in the use of immunosuppressive drugs, apheresis and immunoadsorption
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Provide management plans for physiotherapists for prevention and treatment of arthropathy in haemophilia patients
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Provide advice for management of haemostasis in symptomatic carriers of haemophilia A and B requiring surgery
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Apply their understanding of gene therapy and molecular engineering of FVIII and FIX to clinical management of patients with haemophilia A and B
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Appreciate the issues relating to the provision of haemophilia care in different parts of the world and the difficulties of providing diagnostic and therapeutic services in some countries
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Final self-assessment & evaluation
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