Efficacy and safety of direct oral anticoagulants in the pediatric population: a systematic review and a meta-analysis

ISTH Academy, Faculty / Presenters, 404852

Circulating microRNAs predict recurrence and death following venous thromboembolism

ISTH Academy, Philipp S. Wild, 404853

Venous thromboembolism characteristics, treatment and outcomes in young adults: findings from the Registro Informatizado de Enfermedad TromboEmbólica registry

ISTH Academy, Gili Kenet, 404854

Incidence of bleeding and recurrence in isolated distal deep vein thrombosis: findings from the Venous Thrombosis Registry in Østfold Hospital

ISTH Academy, Faculty / Presenters, 404855

Antibodies against platelet factor 4 and the risk of cerebral venous sinus thrombosis in patients with vaccine-induced immune thrombotic thrombocytopenia

ISTH Academy, Ishac Nazy, 404856

Combined effect of high factor VIII levels and high mean platelet volume on the risk of future incident venous thromboembolism

ISTH Academy, Faculty / Presenters, 404857

High rates of venous thromboembolism among deliveries complicated by cancer

ISTH Academy, Faculty / Presenters, 404858

Contact system and intrinsic pathway activation in patients with advanced pancreatic cancer: a prospective cohort study

ISTH Academy, Faculty / Presenters, 404859

Accuracy of physicians’ intuitive risk estimation in the diagnostic management of pulmonary embolism: an individual patient data meta-analysis

ISTH Academy, Faculty / Presenters, 404860

Prediction of very early major bleeding risk in acute pulmonary embolism: an independent external validation of the Pulmonary Embolism-Syncope, Anemia, and Renal Dysfunction (PE-SARD) bleeding score

ISTH Academy, Faculty / Presenters, 404861

The thrombus proteome in stroke reveals a key role of the innate immune system and new insights associated with its etiology, severity, and prognosis

ISTH Academy, , 404862

Accuracy and interrater agreement of death event adjudications by physician trainees: validation of the ISTH definition of pulmonary embolism-related death in an autopsy cohort

ISTH Academy, Faculty / Presenters, 404863

A unique case of thrombophilia: the role of F9 gene duplication and increased factor IX activity in cerebral venous thrombosis

ISTH Academy, Faculty / Presenters, 404864

Identification of genomic loci regulating platelet plasminogen activator inhibitor-1 in mice

ISTH Academy, Randal J. Westrick, 404865

Inhibition of thrombin-activatable fibrinolysis inhibitor via DS-1040 to accelerate clot lysis in patients with acute pulmonary embolism: a randomized phase 1b study

ISTH Academy, Faculty / Presenters, 404866

Consensus report on flow cytometry for platelet function testing in thrombocytopenic patients: communication from the SSC of the ISTH

ISTH Academy, Faculty / Presenters, 404867

Use of patient-reported outcome measures in patients with venous thromboembolism: communication from the ISTH SSC Subcommittee on Predictive and Diagnostic Variables in Thrombotic Disease

ISTH Academy, Erik Klok, 404868

Survey on antiphospholipid syndrome diagnosis and antithrombotic treatment in patients with ischemic stroke, other brain ischemic injury, or arterial thromboembolism in other sites: communication from ISTH SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies

ISTH Academy, Faculty / Presenters, 404869

“Reclassifying hemophilia to include the definition of outcomes and phenotype as new targets”: comment

ISTH Academy, , 404870

“Reclassifying hemophilia to include the definition of outcomes and phenotype as new targets”: Reply

ISTH Academy, Faculty / Presenters, 404871

Challenges in management of women with type 2B von Willebrand disease during pregnancy and postpartum: evidence from literature and data from International Registry and Physicians Survey- communication from the SSC of the ISTH: comment from Comerford et al.

ISTH Academy, Maeve Crowley, 404872

“C1-inhibitor levels and Venous Thromboembolism: Results from a Mendelian Randomization Study”: comment from Grover et al

ISTH Academy, Faculty / Presenters, 404873

“C1-inhibitor levels and venous thromboembolism: results from a Mendelian randomization study”: reply

ISTH Academy, Faculty / Presenters, 404874

“High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism”: comment from Tanaka et al.

ISTH Academy, Faculty / Presenters, 404875

“High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism”: reply

ISTH Academy, , 404876

ISTH News and Updates: Join the ISTH Today

ISTH Academy, Faculty / Presenters, 404877

OC 76.5 Head-to-head Comparison of Four COVID-19 Vaccines on Platelet Activation, Coagulation and Inflammation. the TREASURE Study

ISTH Academy, Faculty / Presenters, 406164

OC 29.2 The Impact of Pulmonary Embolism on the Long-Term Health Outcomes of COVID-19

ISTH Academy, Faculty / Presenters, 406165

OC 76.3 SARS-CoV-2 Vaccination and Risk of Venous Thrombosis – Case Control Study on Routine Care Data from Dutch General Practitioners

ISTH Academy, Faculty / Presenters, 406166

OC 05.1 Impact of Low Molecular Weight Heparin (LMWH) on SARS-CoV2 Infection: HEPARIN-SARS-CoV2 Clinical Trial

ISTH Academy, Faculty / Presenters, 406167

OC 05.4 Defective Nitric Oxide Production and Increased Reactive Oxygen Species Generation by Platelets from COVID-19 Patients

ISTH Academy, Faculty / Presenters, 406168

OC 05.2 Impact of Heparin on Disease State Transition in Hospitalized, Non-Critically Ill Patients with COVID-19; Secondary Analysis of an International Multi-Platform RCT

ISTH Academy, Faculty / Presenters, 406169

OC 05.3 Incidence and Risk Factors for Venous Thromboembolism in Hospitalized Patients Across Three Major COVID-19 Variants in an Asian Cohort

ISTH Academy, Faculty / Presenters, 406170

OC 29.3 CD147 Plasma Levels in Hospitalised Patients with Covid-19 Pneumonia Predict Illness Severity and In-Hospital Mortality

ISTH Academy, Faculty / Presenters, 406171

OC 29.5 Outcomes of COVID-19 in Persons with Hemophilia: A Propensity ScoreMatched Cohort Study froma US-BasedNational COVIDRegistry

ISTH Academy, Faculty / Presenters, 406172

OC 29.1 Long-Term Outcomes of COVID-19 Associated Venous Thromboembolism (VTE)

ISTH Academy, Faculty / Presenters, 406173

OC 29.4 Impact of Symptom Duration on Clinical Outcomes in Hospitalized, Non-Critically Ill Patients with COVID-19; Secondary Analysis of an International Multi-Platform RCT

ISTH Academy, Faculty / Presenters, 406174

OC 05.5 Hemostatic Biomarkers in Long-Covid Syndrome: A Cross-Sectional Study of 1,310 Covid-19 Survivors

ISTH Academy, Faculty / Presenters, 406175

OC 15.3 Multiplex Quantitation of Coagulation and Fibrinolysis Markers: An Upcoming Approach to Unravel Bleeding and Thrombotic Disorders

ISTH Academy, Faculty / Presenters, 406176

OC 68.5 Plasma N-Glycan Signatures are Associated with a First Event of Venous Thromboembolism

ISTH Academy, Faculty / Presenters, 406177

OC 57.5 Platelet Aggregation and Transcriptomic Profiling Informs Perioperative Bleeding Risk

ISTH Academy, Faculty / Presenters, 406178

OC 68.3 Plasma Levels of Complement C5 are Associated with Thrombin Generation

ISTH Academy, Faculty / Presenters, 406179

OC 15.2 ROTEM Versus Conventional Coagulation Parameter Based Correction of Coagulopathy in Upper Gastrointestinal Bleed in Cirrhotic Patients-Open Label Randomized Control Trial

ISTH Academy, Faculty / Presenters, 406180

OC 23.3 Naked miRNA Mimics and siRNAs Selectively Transfect Megakaryocytes and Platelets In Vivo and Durably Suppress Target Gene Expression to Modulate Megakaryocyte and Platelet Function in Mice

ISTH Academy, Faculty / Presenters, 406181

OC 23.1 Transfusion of RNA-Edited Platelets in a Rodent Model of Polytrauma: A Pilot Study

ISTH Academy, Faculty / Presenters, 406182

OC 57.1 Peptidomics Reveals Expected and Unexpected Proteolytic Events in Plasma Upon Activation of the Coagulation Cascade

ISTH Academy, Faculty / Presenters, 406183

OC 57.3 Genome-Wide Identification of Loci Controlling Plasma Coagulation Factor IX Activity

ISTH Academy, Faculty / Presenters, 406184

OC 68.4 Elucidating New Prothrombotic Factors by Studying the Associations of Laboratory-Measured D-Dimer with the Circulating Blood Proteome

ISTH Academy, Faculty / Presenters, 406185

OC 57.2 Integrated Proteomic and Computational Approach Reveals Determinants of Bleeding Risk in Factor XI Deficiency

ISTH Academy, Faculty / Presenters, 406186

OC 68.1 Platelet RNA-Sequencing in 393 FraminghamHeart Study Participants Reveals Genetic Regulators for a Third of Expressed Transcripts

ISTH Academy, Faculty / Presenters, 406187

OC 68.2 The Atlas of the Hemostatic RNA-Binding Protein Interactome

ISTH Academy, Faculty / Presenters, 406188

OC 23.5 National External Quality Assessment Scheme (NEQAS BC) and Welsh Blood Service (WBS) use Cold-Stored Platelets for External Quality Assessment (EQA) Scheme for Light Transmission Aggregometry (LTA)

ISTH Academy, Faculty / Presenters, 406189

OC 77.1 Development, Validation, and Implementation of a Decision Support Tool for the Screening of Mild Bleeding Disorders

ISTH Academy, Faculty / Presenters, 406190

OC 77.4 Predicting Bethesda Inhibitor Titers in Hemophilia a Patients on the Basis of Screening Assay Results: Ways to Economize the Bethesda Assay

ISTH Academy, Faculty / Presenters, 406191

OC 23.2 In Vitro Generated Megakaryocytes for the Detection of HPAAlloantibodies in Clinical Samples

ISTH Academy, Faculty / Presenters, 406192

OC 57.4 Deciphering Novel Complex Structural Variations in Severe Hemophilia a Patients by Optical Genome Mapping

ISTH Academy, Faculty / Presenters, 406193

OC 77.5 Development of a Rapid and Fully Automated FVIII Inhibitor Assay Insensitive to the Presence of Emicizumab

ISTH Academy, Faculty / Presenters, 406194

OC 15.1 A Novel Point-of-Care Whole Blood Portable Analyzer for Direct Oral Anticoagulant Monitoring

ISTH Academy, Faculty / Presenters, 406195

OC 77.2 Discrepant Low ACL TOP VWF:GP1bR Result is Frequent in Unselected MPN Patients and Does Not Predict Bleeding Risk

ISTH Academy, Faculty / Presenters, 406196

OC 77.3 When is Factor VIII Deficiency Not Hemophilia A? Variant F8 c.1094 A > G, p.Tyr365Cys Illustrates the Utility of Genotyping and the Valueof Disease Specific Expertise in Variant Classification

ISTH Academy, Faculty / Presenters, 406197

OC 15.5 Detection of TIC-Relevant Phenotypes using Bioactive Reagent-Functionalized Dielectric Coagulometry Microsensors

ISTH Academy, Faculty / Presenters, 406198

OC 15.4 ADAMTS13 Results for the SSC Plasma Standard from ECAT and UK NEQAS External Quality Assessment Programmes

ISTH Academy, Faculty / Presenters, 406199

OC 75.1 First US Rare Bleeding Disorder Genotype-Phenotype Registry (ATHN 10) Discovers Many Individuals with Both Novel and Multiple Variants using a Customized 30-Gene Next-Generation Sequencing Panel

ISTH Academy, Faculty / Presenters, 406287

OC 56.5 Detection and Inhibition of Nascent Vascular Calcification with by Protein S Gla-Domain

ISTH Academy, Faculty / Presenters, 406288

OC 49.4 Targeting Myeloid Cell Coagulation Signaling Blocks Map Kinase/TGF-β1 Driven Fibrotic Remodeling, Improves Cardiac Function and Improves Survival in Ischemic Heart Failure

ISTH Academy, Faculty / Presenters, 406289

OC 49.1 3K3A-Activated Protein C Treatment Exerts Anti-Inflammatory and Blood Barrier Stabilizing Effects in the Retina, and Inhibits Choroidal Neovascularization

ISTH Academy, Faculty / Presenters, 406290

OC 49.2 Pharmacological Targeting of the Contact Pathway Attenuates Experimental Autoimmune Encephalomyelitis in Mice

ISTH Academy, Faculty / Presenters, 406291

OC 78.2 Activation of Coagulation Factor XII by Bacterial Lipopolysaccharides

ISTH Academy, Faculty / Presenters, 406292

OC 56.3 Platelets Transfected with a KRASG12D-Silencing siRNA Reduce Pancreatic Tumor Mass In Vivo in Mice

ISTH Academy, Faculty / Presenters, 406293

OC 56.1 Platelets as Versatile Effectors of Thromboinflammation: An MPN Multi-Omics Collaborative

ISTH Academy, Faculty / Presenters, 406294

OC 78.1 Immunomodulatory and Hemostatic Role of Platelets in the Type 2 Inflammatory Response to Schistosoma Mansoni

ISTH Academy, Faculty / Presenters, 406295

OC 78.5 Systemic Snakebite Envenoming Causes Histone-Induced Thrombocytopaenia

ISTH Academy, Faculty / Presenters, 406296

OC 49.3 Modulating Platelet-Microglial Complexes to Limit Neuroinflammation Post-Ischemic Stroke

ISTH Academy, Faculty / Presenters, 406297

OC 56.4 GPVI-Activated Platelets Drive the Neutrophil Profibrotic Function in Systemic Sclerosis

ISTH Academy, Faculty / Presenters, 406298

OC 78.3 Interferon-Induced Transmembrane Protein 3 in Platelets Mediates Granule Secretion, Thrombosis, and Pathophysiological Outcomes in Sepsis

ISTH Academy, Faculty / Presenters, 406299

OC 49.5 Platelet-Derived LTB4 Mediates Neutrophil Recruitment

ISTH Academy, Faculty / Presenters, 406300

OC 78.4 Thrombocytopenia Independently Leads to Monocyte Immune Dysfunction in Sepsis

ISTH Academy, Faculty / Presenters, 406301

OC 55.3 Inflammasome Activation in Vaccine-Induced Thrombotic Thrombocytopenia (VITT) After Immunization with Adenovirus-Based SARS-CoV-2 Vaccines

ISTH Academy, Faculty / Presenters, 406302

OC 55.4 Recombinant Human anti-PF4 IgGs Regenerated from VITT Sera Activate Platelets and Endothelial Cells

ISTH Academy, Faculty / Presenters, 406303

OC 66.1 Comparative Analysis of Coagulopathy in Baboon Models of Toxigenic Versus Non-Toxigenic Bacillus Anthracis Sepsis

ISTH Academy, Faculty / Presenters, 406304

OC 55.1 Balance between Neutrophil Extracellular Trap Formation and DNase Activity in COVID-19 Patients

ISTH Academy, Faculty / Presenters, 406305

OC 66.2 Neutrophil Extracellular Trap Induced Thrombosis Contribute to Tissue Damage but Not to Virus Resolution during a Respiratory Infection

ISTH Academy, Faculty / Presenters, 406306

OC 55.5 Safe Nucleic Acid Inhibitors that Show Protection Against Immunothrombosis in Sepsis

ISTH Academy, Faculty / Presenters, 406307

OC 47.3 Negative Feedback Control of Coagulation by T Helper Cells in Immunothrombosis

ISTH Academy, Faculty / Presenters, 406308

OC 66.4 Platelet Factor 4 (Pf4) Enhances Bacterial Uptake and Clearance by the Endothelium, Contributing to Improved Outcomes in Sepsis

ISTH Academy, Faculty / Presenters, 406309

OC 47.2 Neutrophil Peptidylarginine Deiminase 4 Promotes Obesity-Induced Systemic Inflammation in Mice

ISTH Academy, Faculty / Presenters, 406310

OC 55.2 Dimethyl Fumarate and 4-Octyl Itaconate are Anticoagulants that Suppress Tissue Factor in Macrophages Via Inhibition of Type I Interferon

ISTH Academy, Faculty / Presenters, 406311

OC 47.1 Neutrophil Integrin α9β1 Promotes Post-Stroke Deep Vein Thrombosis

ISTH Academy, Faculty / Presenters, 406312

OC 66.5 Neutrophil Extracellular Trap Components Differentially Induce S100A8/A9 Expression on Platelets Associated with a Procoagulant Phenotype

ISTH Academy, Faculty / Presenters, 406313

OC 66.3 Lack of Plk3 Results in Reduced Platelet Reactivity that Limits Bacteria Infiltration Into the Blood Following Enteric Infection

ISTH Academy, Faculty / Presenters, 406314

OC 47.4 The Spectrum of Light Exposure Modulates Platelet Function

ISTH Academy, Faculty / Presenters, 406315

OC 47.5 Platelet-Derived Integrin and Tetraspanin-Enriched Tethers (PITTs) Orchestrate Neutrophil Recruitment and Drive Pulmonary Thrombo-Inflammation

ISTH Academy, Faculty / Presenters, 406316

OC 48.2 Dosing, Monitoring, Blood Product Utilization, and Thromboembolic Complications of Four Factor Prothrombin Complex Concentrate: A Retrospective Cohort Study

ISTH Academy, Faculty / Presenters, 406317

OC 48.3 Anticoagulation with Intravenous Direct Thrombin Inhibitors in Pediatric ECMO: A Systematic Review

ISTH Academy, Faculty / Presenters, 406318

OC 67.3 Investigating Biomarkers of Bleeding in Neonates and Infants Undergoing Cardiac Surgery with Cardiopulmonary Bypass using Proteomics

ISTH Academy, Faculty / Presenters, 406319

OC 48.1 FOXO1 and FOXO3 Regulate the Proliferation and Suppressive Function of Regulatory T Cells in Pediatric Immune Thrombocytopenia

ISTH Academy, Faculty / Presenters, 406320

OC 67.1 Characterizing the Differences in Adult and Neonatal Biophysical Platelet Function at the Single Cell Level

ISTH Academy, Faculty / Presenters, 406321

OC 67.2 Extracellular Heme Mediates Cellular Inflammation in the ChoroidPlexus Epithelial Cells Following Preterm Intraventricular Hemorrhage

ISTH Academy, Faculty / Presenters, 406322

OC 48.4 The Throm-PED Registry: Epidemiology and Treatment of Adolescent Thrombosis

ISTH Academy, Faculty / Presenters, 406323

OC 26.3 Main Features of Ischemic Stroke in Patients with Acute Immune-Mediated Thrombotic Thrombocytopenic Purpura

ISTH Academy, Faculty / Presenters, 406339