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PB0908 Therapeutic Efficacy of Platelet-Rich Plasma in Chronic Compression of the Dorsal Root Ganglion in Rat
ISTH Academy, Faculty / Presenters, 407414
PB0909 TREM-Like Transcript-1, a Platelet Receptor, as a Potential Regulator of Hepatic Regeneration Post-Surgical Resection
ISTH Academy, Faculty / Presenters, 407415
PB0898 Comparative Methods of Platelet Aggregation by Light Transmission in Elderly Patients
ISTH Academy, Faculty / Presenters, 407416
PB0899 Connexin 45 is Co-Localized with Coxsackievirus-Adenovirus Receptor Forming Contact Membrane within Platelet Aggregates and Filopodia
ISTH Academy, Faculty / Presenters, 407417
PB0900 Developing Standards to Support Platelets and Platelet Components
ISTH Academy, Faculty / Presenters, 407418
PB0902 The Effect of Hypercortisolism on Platelet Function in Dogs with Cushing's Syndrome
ISTH Academy, Faculty / Presenters, 407419
PB0895 Platelet Activation and Aggregation Assays in Non-Human Primates for the Evaluation of Potential Effects of New Drugs in the Context of Non-Clinical Studies
ISTH Academy, Faculty / Presenters, 407420
PB0896 Time-and Distance-Resolved Robotic Imaging of Fluid Flow in Vertical Microfluidic Strips: A New Technique for Quantitative, Multiparameter Global Measure of Haemostasis
ISTH Academy, Faculty / Presenters, 407421
PB0892 C-3399 Inhibitor of PDI Isoforms with an Attractive Profile of Antiplatelet Action
ISTH Academy, Faculty / Presenters, 407422
PB0893 Characterization of the TLT-1 Fibrinogen Ligand Interaction
ISTH Academy, Faculty / Presenters, 407423
PB0894 Evaluating Platelet Function Post Transfusion with Cold-Stored vs Room Temperature Platelets in Patients with Traumatic Brain Injury
ISTH Academy, Faculty / Presenters, 407424
PB0889 Biodesigned Recombinant Protein Mimicking Activities of Fibrillar Collagen in Primary Haemostasis
ISTH Academy, Faculty / Presenters, 407425
PB0890 Discrimination of Agonists-Stimulated Platelet Phenotypes Depending on Pathogen Inactivation and Storage Temperature in a Blood Bank
ISTH Academy, Faculty / Presenters, 407426
PB0891 Impact of Enhanced Platelet Turnover on Platelet Reactivity in Healthy Humans
ISTH Academy, Faculty / Presenters, 407427
PB0882 Contractility of Megakaryocytes and Platelets: Similarities and Distinctions
ISTH Academy, Faculty / Presenters, 407428
PB0883 Defining the Role of Hepcidin and Ferroportin Interactions in Regulating Platelet Function
ISTH Academy, Faculty / Presenters, 407429
PB0884 Development of a Platform to Study Thrombogenicity of Clinically- Used Stents
ISTH Academy, Faculty / Presenters, 407430
PB0885 β-amyloid Peptide Aβ40 Stimulates Glycoprotein Receptor GPVI Signaling to Generate Procoagulant Platelets
ISTH Academy, Faculty / Presenters, 407431
PB0886 Novel Small-Molecule Inhibitors of Clot Retraction and Thrombin- Induced Platelet Aggregation, That Do Not Inhibit PAR-1-Induced Platelet Aggregation
ISTH Academy, Faculty / Presenters, 407432
PB0888 The Effect of Polyphenols on Platelet Procoagulant Activity and Fibrin Clot Structure
ISTH Academy, Faculty / Presenters, 407433
PB0875 A Parallel Kinetic Monte Carlo Simulation of Human Stenotic Thrombus Growth with Single Platelet Resolution from Plaque Rupture to Occlusion
ISTH Academy, Faculty / Presenters, 407434
PB0876 Different Agonists Stimulate a Unique Signature of Platelet Surface Markers Dependent on Aspirin Status as Determined by Platelet Mass Cytometry
ISTH Academy, Faculty / Presenters, 407435
PB0877 Menopause is Associated with Decreased Platelet Reactivity among Women in the Framingham Heart Study
ISTH Academy, Faculty / Presenters, 407436
PB0878 Platelet-Derived Mitochondria Promote Neutrophil Activation and NETosis
ISTH Academy, Faculty / Presenters, 407437
PB0879 Structural Mechanisms and Kinetics of Blood Clot Contraction from in Silico Modeling
ISTH Academy, Faculty / Presenters, 407438
PB0880 The Brain-Derived Neurotrophic Factor (BDNF) Sex-Dependently Affects Platelet Function in Rats
ISTH Academy, Faculty / Presenters, 407439
PB0881 Thrombin Generation after Initial Cessation of Bleeding is Required for Hemostatic Plug Stability via PAR-Mediated Platelet Activation
ISTH Academy, Faculty / Presenters, 407440
PB0872 MicroRNA-223-3p is a Regulator of Platelet Procoagulant Activity
ISTH Academy, Faculty / Presenters, 407441
PB0873 Small-Molecule Cyclophilin Inhibitors Potently Reduce Platelet Procoagulant Activity
ISTH Academy, Faculty / Presenters, 407442
PB0874 The Ins and Outs of Platelet Contractility during Thrombus Formation
ISTH Academy, Faculty / Presenters, 407443
PB0867 Alpha-2-Macroglobulin Precludes Platelet Aggregation in Response to the Brain-Derived Neurotrophic Factor (BDNF)
ISTH Academy, Faculty / Presenters, 407444
PB0868 Dynamics of Alpha-Granule Secretion and Cytoskeletal Arrangements in Spreading Platelets
ISTH Academy, Faculty / Presenters, 407445
PB0869 Platelet-Derived Microvesicles Have a Reparative Role for Muscle Damage Induced by Hypothermia
ISTH Academy, Faculty / Presenters, 407446
PB0865 Endothelial Extracellular Vesicles Regulate In Situ Pulmonary Thrombosis in Sickle Cell Disease
ISTH Academy, Faculty / Presenters, 407447
PB0870 The Role of Cysteine String Protein-α in Platelet Exocytosis
ISTH Academy, Faculty / Presenters, 407448
PB0866 Glycoprotein VI: An Interesting Target to Prevent Early Stent Thrombosis?
ISTH Academy, Faculty / Presenters, 407449
PB0863 Fatty Acid Oxidation Fuels Agonist-Induced Platelet Activation and Thrombus Formation: Targeting Beta-Oxidation of Fatty Acids as an Effective Anti-Platelet Strategy
ISTH Academy, Faculty / Presenters, 407450
PB0864 Platelet Secretion in Wound Healing: The Essence of α-granule Endocytosis, Biogenesis, and Release Kinetics
ISTH Academy, Faculty / Presenters, 407451
PB0861 Endoplasmic Reticulum (ER) Stress is Increased in Diabetic Platelets and Contributes to Platelet Hyperactivity
ISTH Academy, Faculty / Presenters, 407452
PB0394 Argonaute2 (Ago2) Modulates Megakaryocyte Development and Platelet Reactivity in a Sex-Specific Manner via Suppression of Mitochondrial Genes; Evidence for Diverse RNA Granule Species in Platelets
ISTH Academy, Faculty / Presenters, 407453
PB0395 De Novo Protein Synthesis Capacity of Tumor-Educated Platelets
ISTH Academy, Faculty / Presenters, 407454
PB0393 Storage Associated Changes in Apheresis Platelet Components Using Glycomics
ISTH Academy, Faculty / Presenters, 407455
PB0392 Probing Biosynthetic Pathways of Platelets
ISTH Academy, Faculty / Presenters, 407456
PB0390 Identification of Key Regulators of Procoagulant COAT Platelet Generation by Quantitative Phosphoproteomic Analysis and Phosphoflow
ISTH Academy, Faculty / Presenters, 407457
PB0413 Analyzing Moesin and Human TREM-Like Transcript-1 (hTLT-1) Binding and Interaction
ISTH Academy, Faculty / Presenters, 407458
PB0412 Simulating the Impact of Thrombin on Platelet Function Requires Simultaneous Activation of Both PAR-1 and PAR-4
ISTH Academy, Faculty / Presenters, 407459
PB0411 Platelet Glycoprotein IIb- and IIIa Levels are Altered in Persistently Lupus Anticoagulant Positive Patients with a History of Thrombosis
ISTH Academy, Faculty / Presenters, 407460
PB0410 Difluorinated Thromboxane A2 Reveals Crosstalk between Platelet Activatory and Inhibitory Pathways by Targeting Both the TP and IP Receptor
ISTH Academy, Faculty / Presenters, 407461
PB0409 Inhibition of the p75 Pan Neurotrophic Receptor Partly Inhibits BDNF-Induced Platelet Aggregation
ISTH Academy, Faculty / Presenters, 407462
PB0406 Human Platelets and Megakaryocytes Express Precursor Forms of Neurotrophins and Their Respective Receptors
ISTH Academy, Faculty / Presenters, 407463
PB0408 Regulation of Collagen Binding Integrins by Alpha 7 and C Helix
ISTH Academy, Faculty / Presenters, 407464
PB0405 Characterization of TLT-1 and P-Selectin Double Null Mouse in Hemostatic and Immune Function
ISTH Academy, Faculty / Presenters, 407465
PB0404 A Mouse Model of the PAR4 Sequence Variant P310L Shows Decreased Platelet Reactivity and Thrombosis
ISTH Academy, Faculty / Presenters, 407466
PB0403 A Common Variant in GRK5 Reveals a PAR1-Specific Regulation in Platelets
ISTH Academy, Faculty / Presenters, 407467
PB0401 Inhibition of Thrombin-Mediated GPV Cleavage Ameliorates Bleeding Defects in a Broad Range of Pathological Conditions
ISTH Academy, Faculty / Presenters, 407468
PB0402 The FCγRIIA Receptor Does Not Play a Critical Role in Hemostasis and Thrombosis in the Absence of Immune Complexes
ISTH Academy, Faculty / Presenters, 407469
PB0400 The Janus-Face of Platelet PAR4: Dose-Dependent Host Protective and Detrimental Roles in Influenza a Virus Infection of Mice
ISTH Academy, Faculty / Presenters, 407470
PB0398 Platelet β1 and β3 Integrins Play a Key Role in Hemostasis, Arterial Thrombosis and Tumor Metastasis
ISTH Academy, Faculty / Presenters, 407471
PB0399 The NMDA Receptor Regulates Integrin Activation and Arterial Thrombosis through Store-Operated Ca2+ Entry in Platelets
ISTH Academy, Faculty / Presenters, 407472
PB0397 Differential Requirement for Ligand Valency in the Activation of CLEC-2 in Human and Humanised Mouse Platelets
ISTH Academy, Faculty / Presenters, 407473
PB0429 Potential Difference in Platelet Aggregation between Clinical Dexmedetomidine and Experimental Medetomidine Due to Dose Differences
ISTH Academy, Faculty / Presenters, 407474
PB0427 The Role of Mitochondrial Calcium Uniporter in Platelet Signaling
ISTH Academy, Faculty / Presenters, 407475
PB0425 STING Stimulation Drives a Type-I IFN Response in Megakaryocytes and Potentiates the Activation of Platelets
ISTH Academy, Faculty / Presenters, 407476
PB0423 Protein Phosphatase 1 Alpha from Platelets Dampen Endotoxin- Induced Proinflammatory Signaling and Kidney Tubular Apoptosis and Injury
ISTH Academy, Faculty / Presenters, 407477
PB0424 The Critical Role of Filamin a in the Platelet Shape Change Reaction
ISTH Academy, Faculty / Presenters, 407478
PB0421 Phosphoproteomics and Systems Analysis Reveal Protein Kinase C Theta (PKCfɵ) Signaling Events Associated with the Generation of Procoagulant Platelets
ISTH Academy, Faculty / Presenters, 407479
PB0422 The Piperazinyl-Purine Analogue MK177 is a Bifunctional Drug with Promising Anti-Ischemic and Anti-Thrombotic Potential
ISTH Academy, Faculty / Presenters, 407480
PB0416 Platelet Polyphosphate Activates NFκB Signaling to Induce Myofibroblast Differentiation
ISTH Academy, Faculty / Presenters, 407481
PB0419 The Molecular Basis of Carrageenan-Induced Thrombosis Involves Platelet Activation via C-Type Lectin Like Receptor 2 (CLEC-2)
ISTH Academy, Faculty / Presenters, 407482
PB0415 The Role of Filamin a in Platelet Thromboxane A2 Secretion
ISTH Academy, Faculty / Presenters, 407483
PB1411 Study of Endothelial Dysfunction in Patients with Unprovoked Venous Thromboembolism through Endothelial Colony-Forming Cell In Vitro Characterization
ISTH Academy, Faculty / Presenters, 407484
PB1416 Challenge in the Investigation of Patients with Bleeding: Delayed Diagnosis of Vascular Ehlers-Danlos Syndrome
ISTH Academy, Faculty / Presenters, 407485
PB1407 Colonization of Fibrin Clot Formed by Cancer Cells in Tumor Microenvironment. A Mechanism Potentially Related with Resistance to the Anticancer Treatment
ISTH Academy, Faculty / Presenters, 407486
PB1410 The Association between Microvascular Health and Coagulation Parameters: The Netherlands Epidemiology of Obesity Study
ISTH Academy, Faculty / Presenters, 407487
PB1409 The Impact of Platelets on Inflammation and Extracellular Matrix Remodelling in Abdominal Aortic Aneurysm Formation
ISTH Academy, Faculty / Presenters, 407488
PB1404 Comparison of Cardiovascular and Respiratory Toxicity of Heparin Antidotes: Protamine Sulfate, PER977 and Heparin-Binding Copolymer (HBC)
ISTH Academy, Faculty / Presenters, 407489
PB1405 Development of a Method for the Detection of the JAK2V617F Mutation in Human Circulating Endothelial Cells
ISTH Academy, Faculty / Presenters, 407490
PB1406 Gastrointestinal Bleeding due to Angiodysplasia in Patients with von Willebrand Disease and Glanzmann Thrombasthenia
ISTH Academy, Faculty / Presenters, 407491
PB1400 Differential Effects of Vitamin-K Dependent Proteins on Vascular Calcification - Chemical Protein Synthesis and Bulk RNA Sequencing to Unravel Cellular Pathways
ISTH Academy, Faculty / Presenters, 407492
PB1401 Impact of Platelet Activation on Tau Protein
ISTH Academy, Faculty / Presenters, 407493
PB1402 NBEAL2 and the Intragranular Proteoglycan, Serglycin, Both Contribute to the Initiation and Progression of Aortic Aneurysms
ISTH Academy, Faculty / Presenters, 407494
PB1403 Physiological Levels of Vascular Turbulence Increase Hemolysis with Implications for Vascular Dysfunction in Sickle Cell Disease
ISTH Academy, Faculty / Presenters, 407495
PB1399 Automated Segmentation and Quantitative Analysis of Weibel-Palade Body Morphology, Localization and Content Using CellProfiler
ISTH Academy, Faculty / Presenters, 407496
PB1397 Platelet Activating and Fibrin Generating Properties of Distinct Vascular Smooth Muscle Cell Phenotypes
ISTH Academy, Faculty / Presenters, 407497
PB1398 RBC-Derived Transglutaminase-2 Affects Thrombus Formation
ISTH Academy, Faculty / Presenters, 407498
PB1422 Differential Expression of Proteins from Cultured Endothelial Cells Exposed to Serum from Patients with Acute Graft versus Host Disease Sensitive or Refractory to Corticosteroid Treatment
ISTH Academy, Faculty / Presenters, 407499
PB1417 Pleiotropic Roles of FVIII: New Insight in Endothelial Cell Functionality
ISTH Academy, Faculty / Presenters, 407500
PB1427 Reduced ADAMTS13 Activity in Staphylococcus Aureus Bacteremia is Associated with Neutrophil-Mediated Citrullination
ISTH Academy, Faculty / Presenters, 407501
PB1426 Studies of Streptozotocin-Induced Hyperglycemia on the Host Response to Sepsis
ISTH Academy, Faculty / Presenters, 407502
PB1425 High Cell-free (cf)DNA in Patients with Myelofibrosis (MF) is Associated with Adverse Clinical Outcomes, Activation of the AIM2 Inflammasome and Elevated Levels of Inflammasome-Related Cytokine IL-18
ISTH Academy, Faculty / Presenters, 407503
PB1424 PCF11 is a Central Hub in the Regulation of Inflammation in an Animal Model of Septicemia
ISTH Academy, Faculty / Presenters, 407504
PB1430 Vascular Injury Derived Exosomes are Involved in Break in Tolerance to Vascular Autoantigens
ISTH Academy, Faculty / Presenters, 407505
PB1429 NETs Promote Gasdermin-D-Dependent Pulmonary Thrombosis in Mice Exposed to Cigarette Smoke and Flu
ISTH Academy, Faculty / Presenters, 407506
PB1432 Small Interfering RNA-mediated Inhibition of Endothelial Von Willebrand Factor in Pro-Atherothrombotic Mice
ISTH Academy, Faculty / Presenters, 407507
PB1431 Effect of Allele-Selective Silencing of von Willebrand Factor in Mice on Experimental Bleeding and Thrombosis Models
ISTH Academy, Faculty / Presenters, 407508
PB1436 PAR1 Knockout Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells Display Higher Tissue Factor-Dependent Thrombin Generation Compared to Wild Type
ISTH Academy, Faculty / Presenters, 407509
PB1435 Canonical Activation of Protease-Activated Receptor-1 Drives Experimental Liver Fibrosis
ISTH Academy, Faculty / Presenters, 407510
PB1433 Opposing Effects of Canonical and Non-Canonical PAR-1 Activation in Experimental Diet-Induced Obesity and Fatty Liver Disease
ISTH Academy, Faculty / Presenters, 407511
PB1434 Inhibition of Thrombin Receptor PAR-1 in Endothelial Colony Forming Cells Modify Their Stemness and Vasculogenic Properties
ISTH Academy, Faculty / Presenters, 407512
PB0441 Did the ISTH 2020 Guidance Resolve the Inclution of Patients?
ISTH Academy, Faculty / Presenters, 407513

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