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PB0884 Development of a Platform to Study Thrombogenicity of Clinically- Used Stents
ISTH Academy, Faculty / Presenters, 407430
PB0885 β-amyloid Peptide Aβ40 Stimulates Glycoprotein Receptor GPVI Signaling to Generate Procoagulant Platelets
ISTH Academy, Faculty / Presenters, 407431
PB0886 Novel Small-Molecule Inhibitors of Clot Retraction and Thrombin- Induced Platelet Aggregation, That Do Not Inhibit PAR-1-Induced Platelet Aggregation
ISTH Academy, Faculty / Presenters, 407432
PB0888 The Effect of Polyphenols on Platelet Procoagulant Activity and Fibrin Clot Structure
ISTH Academy, Faculty / Presenters, 407433
PB0875 A Parallel Kinetic Monte Carlo Simulation of Human Stenotic Thrombus Growth with Single Platelet Resolution from Plaque Rupture to Occlusion
ISTH Academy, Faculty / Presenters, 407434
PB0876 Different Agonists Stimulate a Unique Signature of Platelet Surface Markers Dependent on Aspirin Status as Determined by Platelet Mass Cytometry
ISTH Academy, Faculty / Presenters, 407435
PB0877 Menopause is Associated with Decreased Platelet Reactivity among Women in the Framingham Heart Study
ISTH Academy, Faculty / Presenters, 407436
PB0878 Platelet-Derived Mitochondria Promote Neutrophil Activation and NETosis
ISTH Academy, Faculty / Presenters, 407437
PB0879 Structural Mechanisms and Kinetics of Blood Clot Contraction from in Silico Modeling
ISTH Academy, Faculty / Presenters, 407438
PB0880 The Brain-Derived Neurotrophic Factor (BDNF) Sex-Dependently Affects Platelet Function in Rats
ISTH Academy, Faculty / Presenters, 407439
PB0881 Thrombin Generation after Initial Cessation of Bleeding is Required for Hemostatic Plug Stability via PAR-Mediated Platelet Activation
ISTH Academy, Faculty / Presenters, 407440
PB0872 MicroRNA-223-3p is a Regulator of Platelet Procoagulant Activity
ISTH Academy, Faculty / Presenters, 407441
PB0873 Small-Molecule Cyclophilin Inhibitors Potently Reduce Platelet Procoagulant Activity
ISTH Academy, Faculty / Presenters, 407442
PB0874 The Ins and Outs of Platelet Contractility during Thrombus Formation
ISTH Academy, Faculty / Presenters, 407443
PB0867 Alpha-2-Macroglobulin Precludes Platelet Aggregation in Response to the Brain-Derived Neurotrophic Factor (BDNF)
ISTH Academy, Faculty / Presenters, 407444
PB0868 Dynamics of Alpha-Granule Secretion and Cytoskeletal Arrangements in Spreading Platelets
ISTH Academy, Faculty / Presenters, 407445
PB0869 Platelet-Derived Microvesicles Have a Reparative Role for Muscle Damage Induced by Hypothermia
ISTH Academy, Faculty / Presenters, 407446
PB0865 Endothelial Extracellular Vesicles Regulate In Situ Pulmonary Thrombosis in Sickle Cell Disease
ISTH Academy, Faculty / Presenters, 407447
PB0870 The Role of Cysteine String Protein-α in Platelet Exocytosis
ISTH Academy, Faculty / Presenters, 407448
PB0866 Glycoprotein VI: An Interesting Target to Prevent Early Stent Thrombosis?
ISTH Academy, Faculty / Presenters, 407449
PB0863 Fatty Acid Oxidation Fuels Agonist-Induced Platelet Activation and Thrombus Formation: Targeting Beta-Oxidation of Fatty Acids as an Effective Anti-Platelet Strategy
ISTH Academy, Faculty / Presenters, 407450
PB0864 Platelet Secretion in Wound Healing: The Essence of α-granule Endocytosis, Biogenesis, and Release Kinetics
ISTH Academy, Faculty / Presenters, 407451
PB0861 Endoplasmic Reticulum (ER) Stress is Increased in Diabetic Platelets and Contributes to Platelet Hyperactivity
ISTH Academy, Faculty / Presenters, 407452
PB0394 Argonaute2 (Ago2) Modulates Megakaryocyte Development and Platelet Reactivity in a Sex-Specific Manner via Suppression of Mitochondrial Genes; Evidence for Diverse RNA Granule Species in Platelets
ISTH Academy, Faculty / Presenters, 407453
PB0395 De Novo Protein Synthesis Capacity of Tumor-Educated Platelets
ISTH Academy, Faculty / Presenters, 407454
PB0393 Storage Associated Changes in Apheresis Platelet Components Using Glycomics
ISTH Academy, Faculty / Presenters, 407455
PB0392 Probing Biosynthetic Pathways of Platelets
ISTH Academy, Faculty / Presenters, 407456
PB0390 Identification of Key Regulators of Procoagulant COAT Platelet Generation by Quantitative Phosphoproteomic Analysis and Phosphoflow
ISTH Academy, Faculty / Presenters, 407457
PB0413 Analyzing Moesin and Human TREM-Like Transcript-1 (hTLT-1) Binding and Interaction
ISTH Academy, Faculty / Presenters, 407458
PB0412 Simulating the Impact of Thrombin on Platelet Function Requires Simultaneous Activation of Both PAR-1 and PAR-4
ISTH Academy, Faculty / Presenters, 407459
PB0411 Platelet Glycoprotein IIb- and IIIa Levels are Altered in Persistently Lupus Anticoagulant Positive Patients with a History of Thrombosis
ISTH Academy, Faculty / Presenters, 407460
PB0410 Difluorinated Thromboxane A2 Reveals Crosstalk between Platelet Activatory and Inhibitory Pathways by Targeting Both the TP and IP Receptor
ISTH Academy, Faculty / Presenters, 407461
PB0409 Inhibition of the p75 Pan Neurotrophic Receptor Partly Inhibits BDNF-Induced Platelet Aggregation
ISTH Academy, Faculty / Presenters, 407462
PB0406 Human Platelets and Megakaryocytes Express Precursor Forms of Neurotrophins and Their Respective Receptors
ISTH Academy, Faculty / Presenters, 407463
PB0408 Regulation of Collagen Binding Integrins by Alpha 7 and C Helix
ISTH Academy, Faculty / Presenters, 407464
PB0405 Characterization of TLT-1 and P-Selectin Double Null Mouse in Hemostatic and Immune Function
ISTH Academy, Faculty / Presenters, 407465
PB0404 A Mouse Model of the PAR4 Sequence Variant P310L Shows Decreased Platelet Reactivity and Thrombosis
ISTH Academy, Faculty / Presenters, 407466
PB0403 A Common Variant in GRK5 Reveals a PAR1-Specific Regulation in Platelets
ISTH Academy, Faculty / Presenters, 407467
PB0401 Inhibition of Thrombin-Mediated GPV Cleavage Ameliorates Bleeding Defects in a Broad Range of Pathological Conditions
ISTH Academy, Faculty / Presenters, 407468
PB0402 The FCγRIIA Receptor Does Not Play a Critical Role in Hemostasis and Thrombosis in the Absence of Immune Complexes
ISTH Academy, Faculty / Presenters, 407469
PB0400 The Janus-Face of Platelet PAR4: Dose-Dependent Host Protective and Detrimental Roles in Influenza a Virus Infection of Mice
ISTH Academy, Faculty / Presenters, 407470
PB0398 Platelet β1 and β3 Integrins Play a Key Role in Hemostasis, Arterial Thrombosis and Tumor Metastasis
ISTH Academy, Faculty / Presenters, 407471
PB0399 The NMDA Receptor Regulates Integrin Activation and Arterial Thrombosis through Store-Operated Ca2+ Entry in Platelets
ISTH Academy, Faculty / Presenters, 407472
PB0397 Differential Requirement for Ligand Valency in the Activation of CLEC-2 in Human and Humanised Mouse Platelets
ISTH Academy, Faculty / Presenters, 407473
PB0429 Potential Difference in Platelet Aggregation between Clinical Dexmedetomidine and Experimental Medetomidine Due to Dose Differences
ISTH Academy, Faculty / Presenters, 407474
PB0427 The Role of Mitochondrial Calcium Uniporter in Platelet Signaling
ISTH Academy, Faculty / Presenters, 407475
PB0425 STING Stimulation Drives a Type-I IFN Response in Megakaryocytes and Potentiates the Activation of Platelets
ISTH Academy, Faculty / Presenters, 407476
PB0423 Protein Phosphatase 1 Alpha from Platelets Dampen Endotoxin- Induced Proinflammatory Signaling and Kidney Tubular Apoptosis and Injury
ISTH Academy, Faculty / Presenters, 407477
PB0424 The Critical Role of Filamin a in the Platelet Shape Change Reaction
ISTH Academy, Faculty / Presenters, 407478
PB0421 Phosphoproteomics and Systems Analysis Reveal Protein Kinase C Theta (PKCfɵ) Signaling Events Associated with the Generation of Procoagulant Platelets
ISTH Academy, Faculty / Presenters, 407479
PB0422 The Piperazinyl-Purine Analogue MK177 is a Bifunctional Drug with Promising Anti-Ischemic and Anti-Thrombotic Potential
ISTH Academy, Faculty / Presenters, 407480
PB0416 Platelet Polyphosphate Activates NFκB Signaling to Induce Myofibroblast Differentiation
ISTH Academy, Faculty / Presenters, 407481
PB0419 The Molecular Basis of Carrageenan-Induced Thrombosis Involves Platelet Activation via C-Type Lectin Like Receptor 2 (CLEC-2)
ISTH Academy, Faculty / Presenters, 407482
PB0415 The Role of Filamin a in Platelet Thromboxane A2 Secretion
ISTH Academy, Faculty / Presenters, 407483
PB1411 Study of Endothelial Dysfunction in Patients with Unprovoked Venous Thromboembolism through Endothelial Colony-Forming Cell In Vitro Characterization
ISTH Academy, Faculty / Presenters, 407484
PB1416 Challenge in the Investigation of Patients with Bleeding: Delayed Diagnosis of Vascular Ehlers-Danlos Syndrome
ISTH Academy, Faculty / Presenters, 407485
PB1407 Colonization of Fibrin Clot Formed by Cancer Cells in Tumor Microenvironment. A Mechanism Potentially Related with Resistance to the Anticancer Treatment
ISTH Academy, Faculty / Presenters, 407486
PB1410 The Association between Microvascular Health and Coagulation Parameters: The Netherlands Epidemiology of Obesity Study
ISTH Academy, Faculty / Presenters, 407487
PB1409 The Impact of Platelets on Inflammation and Extracellular Matrix Remodelling in Abdominal Aortic Aneurysm Formation
ISTH Academy, Faculty / Presenters, 407488
PB1404 Comparison of Cardiovascular and Respiratory Toxicity of Heparin Antidotes: Protamine Sulfate, PER977 and Heparin-Binding Copolymer (HBC)
ISTH Academy, Faculty / Presenters, 407489
PB1405 Development of a Method for the Detection of the JAK2V617F Mutation in Human Circulating Endothelial Cells
ISTH Academy, Faculty / Presenters, 407490
PB1406 Gastrointestinal Bleeding due to Angiodysplasia in Patients with von Willebrand Disease and Glanzmann Thrombasthenia
ISTH Academy, Faculty / Presenters, 407491
PB1400 Differential Effects of Vitamin-K Dependent Proteins on Vascular Calcification - Chemical Protein Synthesis and Bulk RNA Sequencing to Unravel Cellular Pathways
ISTH Academy, Faculty / Presenters, 407492
PB1401 Impact of Platelet Activation on Tau Protein
ISTH Academy, Faculty / Presenters, 407493
PB1402 NBEAL2 and the Intragranular Proteoglycan, Serglycin, Both Contribute to the Initiation and Progression of Aortic Aneurysms
ISTH Academy, Faculty / Presenters, 407494
PB1403 Physiological Levels of Vascular Turbulence Increase Hemolysis with Implications for Vascular Dysfunction in Sickle Cell Disease
ISTH Academy, Faculty / Presenters, 407495
PB1399 Automated Segmentation and Quantitative Analysis of Weibel-Palade Body Morphology, Localization and Content Using CellProfiler
ISTH Academy, Faculty / Presenters, 407496
PB1397 Platelet Activating and Fibrin Generating Properties of Distinct Vascular Smooth Muscle Cell Phenotypes
ISTH Academy, Faculty / Presenters, 407497
PB1398 RBC-Derived Transglutaminase-2 Affects Thrombus Formation
ISTH Academy, Faculty / Presenters, 407498
PB1422 Differential Expression of Proteins from Cultured Endothelial Cells Exposed to Serum from Patients with Acute Graft versus Host Disease Sensitive or Refractory to Corticosteroid Treatment
ISTH Academy, Faculty / Presenters, 407499
PB1417 Pleiotropic Roles of FVIII: New Insight in Endothelial Cell Functionality
ISTH Academy, Faculty / Presenters, 407500
PB1427 Reduced ADAMTS13 Activity in Staphylococcus Aureus Bacteremia is Associated with Neutrophil-Mediated Citrullination
ISTH Academy, Faculty / Presenters, 407501
PB1426 Studies of Streptozotocin-Induced Hyperglycemia on the Host Response to Sepsis
ISTH Academy, Faculty / Presenters, 407502
PB1425 High Cell-free (cf)DNA in Patients with Myelofibrosis (MF) is Associated with Adverse Clinical Outcomes, Activation of the AIM2 Inflammasome and Elevated Levels of Inflammasome-Related Cytokine IL-18
ISTH Academy, Faculty / Presenters, 407503
PB1424 PCF11 is a Central Hub in the Regulation of Inflammation in an Animal Model of Septicemia
ISTH Academy, Faculty / Presenters, 407504
PB1430 Vascular Injury Derived Exosomes are Involved in Break in Tolerance to Vascular Autoantigens
ISTH Academy, Faculty / Presenters, 407505
PB1429 NETs Promote Gasdermin-D-Dependent Pulmonary Thrombosis in Mice Exposed to Cigarette Smoke and Flu
ISTH Academy, Faculty / Presenters, 407506
PB1432 Small Interfering RNA-mediated Inhibition of Endothelial Von Willebrand Factor in Pro-Atherothrombotic Mice
ISTH Academy, Faculty / Presenters, 407507
PB1431 Effect of Allele-Selective Silencing of von Willebrand Factor in Mice on Experimental Bleeding and Thrombosis Models
ISTH Academy, Faculty / Presenters, 407508
PB1436 PAR1 Knockout Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells Display Higher Tissue Factor-Dependent Thrombin Generation Compared to Wild Type
ISTH Academy, Faculty / Presenters, 407509
PB1435 Canonical Activation of Protease-Activated Receptor-1 Drives Experimental Liver Fibrosis
ISTH Academy, Faculty / Presenters, 407510
PB1433 Opposing Effects of Canonical and Non-Canonical PAR-1 Activation in Experimental Diet-Induced Obesity and Fatty Liver Disease
ISTH Academy, Faculty / Presenters, 407511
PB1434 Inhibition of Thrombin Receptor PAR-1 in Endothelial Colony Forming Cells Modify Their Stemness and Vasculogenic Properties
ISTH Academy, Faculty / Presenters, 407512
PB0441 Did the ISTH 2020 Guidance Resolve the Inclution of Patients?
ISTH Academy, Faculty / Presenters, 407513
PB0437 Concordance of Phosphatidylserine/Prothrombin and APhL Antibodies Associated with Antiphospholipid Syndrome-Associated Pregnancy Morbidity
ISTH Academy, Faculty / Presenters, 407514
PB0439 Deep Vein Thrombosis in a Celiac Patient is Complicated by Her Anti-Phospholipid Antibody
ISTH Academy, Faculty / Presenters, 407515
PB0436 Long-Term Use of Fondaparinux in Patients with Thrombotic Antiphospholipid Syndrome - A Retrospective Audit of Clinical Outcomes
ISTH Academy, Faculty / Presenters, 407516
PB0435 Interference in Point-of-Care International Normalized Ratio Monitoring in Patients with Lupus Anticoagulant is Correlated with Anti-β2-Glycoprotein I Antibody Titers
ISTH Academy, Faculty / Presenters, 407517
PB0434 Role of Contact Activation Pathway in Antiphospholipid Syndrome: A Case-Control Study
ISTH Academy, Faculty / Presenters, 407518
PB0432 Identification of a Subset of Thrombotic Antiphospholipid Syndrome Patients with Significant Discordance in Paired Capillary- and Venous- Monitoring with an International Normalized Ratio
ISTH Academy, Faculty / Presenters, 407519
PB0431 Insights on Venous Thromboembolism and Antiphospholipid Antibody Syndrome by 1H-NMR
ISTH Academy, Faculty / Presenters, 407520
PB0430 Treatment of APS Patients with Rivaroxaban or Apixaban: A Cohort Single-Center Study
ISTH Academy, Faculty / Presenters, 407521
PB0443 Innovative Non-Isocyanate Polyurethane-Derived Hemocompatible Polymers for Blood-Contacting Medical Devices
ISTH Academy, Faculty / Presenters, 407522
PB0983 Assessing Hypercoagulability and VTE Risk Using Thromboelastography and Khorana Score in Women Receiving Chemotherapy for Breast and Gynecological Cancer
ISTH Academy, Faculty / Presenters, 407523
PB0979 Significantly Increased CVC Replacement in Patients with Both Symptomatic and Incidental Venous Thrombotic Events in Pediatric Cancer Patients: A Population-Based Study
ISTH Academy, Faculty / Presenters, 407524
PB0984 Prediction of Lung Cancer-Associated Venous Thromboembolism in Middle and Low Income Countries: The N & N Score
ISTH Academy, Faculty / Presenters, 407525
PB0980 TINzaparin PROphylaxis in Patients with Metastatic COLorectal Cancer (PROTINCOL)
ISTH Academy, Faculty / Presenters, 407526
PB0973 Perioperative Coagulation Profile in Major Liver Resection for Cancer
ISTH Academy, Faculty / Presenters, 407527
PB0974 Safety of Direct Oral Anticoagulant (DOAC) in Adult Patients with Venous Thromboembolism or Non-Valvular Atrial Fibrillation in the Context of Urogenital and Gynecological Cancer: Systematic Review
ISTH Academy, Faculty / Presenters, 407528
PB0976 Usefulness of Different Clinical Risk Scores to Predict In-Hospital Mortality in Patients with Acute Pulmonary Embolism and Cancer
ISTH Academy, Faculty / Presenters, 407529
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