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Understanding the processes behind unwarranted blood clotting, as well as its diagnosis and management, can have far reaching consequences - from preventing deep venous thrombosis in healthy young people, to saving the lives of patients with pulmonary embolism.

The course content is provided to all who are looking for a working knowledge of thrombosis: from clinicians working with thrombosis patients and those training in internal medicine, hematology or vascular biology to (bio) medical students and researchers.

The Venous Thrombosis course takes you through many aspects of venous thrombosis, including its basis in the coagulation system, etiology and prognosis, diagnosis and management. As well as educational, the modules are interactive and multimedia, featuring a number of fascinating key lectures from leading experts in their field, contemporary conceptual animations and traditional, paper-based learning.

The course is segmented in the following 9 modules :
1. The coagulation system by Ken Mann
2. Incidence and risk factors of venous thrombosis by Frits Rosendaal
3. Diagnosis of Venous Thrombosis by Phil Wells
4. Thrombosis during Pregnancy and the Postpartum Period by Saskia Middeldorp
5. Thrombosis During Early Life and Childhood by Paul Monagle
6. Anticoagulant Drugs by Trevor Baglin
7. Treatment of Venous Thrombosis by Clive Kearon
8. Prevention of Venous Thrombosis (available soon)
      a. In medical patients
      b. In surgical patients
9. Laboratory tests (available soon)
      a. Diagnosis of thrombophilia
      b. Monitoring of anticoagulant therapy

Students should be able to:

1. Have basic knowledge of the mechanisms of thrombus formation and the role of endothelium, platelets and coagulation factors
2. Be familiar with the size of the absolute risk (incidence rate) of venous thrombosis, both for first and for recurrent events
3. Know and recognize risk factors for venous thrombosis and have a feeling for their strength (relative risk)
4. Have knowledge of ways to prevent venous thrombosis in hospitalized medical patients
5. Have knowledge of ways to prevent venous thrombosis in hospitalized surgical patients
6. Be able to decide which pregnant women need to receive thromboprophylaxis
7. Know how to treat pregnant women with DVT or PE
8. Recognize signs and symptoms of DVT and PE
9. Appreciate the role of clinical decision rules in establishing a diagnosis of DVT or PE
10. Be familiar with testing modalities for diagnosis of DVT and PE
11. Appreciate the role of d-dimer testing in diagnosing DVT and PE
12. Have knowledge of the differential diagnosis of DVT and PE
13. Decide whether outpatient or hospital treatment is required for a patient with DVTv
14. Know what anticoagulant regimens can be used to treat patients with DVT or PE
15. Know how to monitor patients on anticoagulation
16. Consider the duration of anticoagulation therapy based on the presence or absence of certain risk factors
17. Know the risk of side-effects of anticoagulation therapy
18. Be aware of treatment options for patients who have contraindications to anticoagulation
19. Argue on the pros and cons of thrombophilia testing
Internists, (Orthopedic) surgeons, Trainees for these specialties, Young investigators in the field of hemostasis and thrombosis, Junior medical staff, Laboratory technicians, Hematologists, Generalists (GPs, internists)

The accreditation for this e-learning program has expired.




Suzanne Cannegieter
Editor
No relevant financial relationships to disclose


Willem M Lijfering
Editor
No relevant financial relationships to disclose


Kenneth Mann
Haematologic Technologies Inc.: Chairman, XO1 Scientific Advisory Board: Advisor, IDEC Biogen: Conference Consultant, Bayer: Advisory Board, Vascular Solutions: Consultant, CSL Behring: Consultant, Pfizer: Consultant, The Medicines Company: Consultant


Frits Rosendaal
No conflicts of interest to disclose
Module 1: The Coagulation System
Module 2: Incidence and Risk Factors of Venous Thrombosis
Module 3: Diagnosis of Deep Venous Thrombosis
Module 4: Thrombosis during Pregnancy and the Postpartum Period
Module 5: Thrombosis During Early Life and Childhood
Module 6: Anticoagulant Drugs
Module 7: Treatment of Venous Thrombosis
Module 8 - Prophylaxis of Venous Thrombosis
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